Mittmann Nicole, Knowles Sandra
HOPE Research Centre, Division of Clinical Pharmacology, Sunnybrook Health Sciences Centre, Toronto, Canada.
Can J Clin Pharmacol. 2009 Winter;16(1):e171-7. Epub 2009 Feb 25.
Pharmacy and Therapeutics (P&T) committees have traditionally evaluated and developed policies for the clinical use of medications and for ensuring safe and effective drug use and administration.
The objective of this study was to determine the current activities of hospital P&T committees across Canada.
Surveys were mailed to 856 (693 English, 163 French translations) Canadian hospitals (acute, chronic or rehabilitation) across Canada. Questions consisted of information on P&T membership, scope and responsibilities. Completed surveys were returned by fax. All data was entered into Excel and analyzed for descriptive statistics.
123 surveys were returned, representing 207 hospitals, for an effective response rate of 24%. Four hospitals returned incomplete surveys. Surveys were returned from all areas of Canada, except the territories. On average, P&T committees met six times per year. The average size of the committees was 11 members, with physicians comprising half the membership. Pharmacists and nurses had equal representation; other members were community representatives, dieticians, quality assurance personnel and/or administrators. The top responsibilities of the P&T committee were inpatient formulary management (93% of respondents), drug-use policy making (92%), adverse drug reaction monitoring (83%), patient safety (80%) and drug-use monitoring (80%). Subcommittees were utilized by 46% of P&T committees including antimicrobial (38%), medication safety (25%) and nutrition (14%). Economic evaluations were most frequently completed by a pharmacist who had some previous pharmacoeconomic experience.
This survey reports on the current status and responsibilities, namely formulary management and policy making, of P&T committees in Canada.
药学与治疗学（P&T）委员会传统上负责评估和制定药物临床使用政策，以确保药物使用和管理的安全有效。
本研究的目的是确定加拿大各地医院P&T委员会的当前活动。
向加拿大各地的856家（693家英文医院，163家法文翻译医院）加拿大医院（急性、慢性或康复医院）邮寄调查问卷。问题包括P&T成员、范围和职责的信息。完成的调查问卷通过传真返回。所有数据都输入到Excel中，并进行描述性统计分析。
共返回123份调查问卷，代表207家医院，有效回复率为24%。四家医院返回的调查问卷不完整。除了各地区外，加拿大所有地区都有调查问卷返回。P&T委员会平均每年开会六次。委员会的平均规模为11名成员，其中医生占成员总数的一半。药剂师和护士的代表人数相等；其他成员包括社区代表、营养师、质量保证人员和/或管理人员。P&T委员会的首要职责是住院患者处方集管理（93%的受访者）、药物使用政策制定（92%）、药物不良反应监测（83%）、患者安全（80%）和药物使用监测（80%）。46%的P&T委员会设有小组委员会，包括抗菌药物（38%）、用药安全（25%）和营养（14%）。经济评估最常由具有一定药物经济学经验的药剂师完成。
本调查报道了加拿大P&T委员会的当前状况和职责，即处方集管理和政策制定。
