Protein quality control as a strategy for cellular regulation: lessons from ubiquitin-mediated regulation of the sterol pathway.
作者信息
Hampton Randolph Y, Garza Renee M
机构信息
Division of Biological Sciences, University of California at San Diego, La Jolla, California 92093, USA.
出版信息
Chem Rev. 2009 Apr;109(4):1561-74. doi: 10.1021/cr800544v.
Abstract
摘要
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Protein secretion and membrane insertion systems in bacteria and eukaryotic organelles.细菌和真核细胞器中的蛋白质分泌与膜插入系统。
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HPV E6, E6AP and cervical cancer.人乳头瘤病毒E6、E6相关蛋白与宫颈癌
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Mass spectrometric analysis of type 1 inositol 1,4,5-trisphosphate receptor ubiquitination.1型肌醇1,4,5-三磷酸受体泛素化的质谱分析
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Cue1p is an activator of Ubc7p E2 activity in vitro and in vivo.Cue1p在体外和体内都是Ubc7p E2活性的激活剂。
J Biol Chem. 2008 May 9;283(19):12797-810. doi: 10.1074/jbc.M801122200. Epub 2008 Mar 5.
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Common and specific mechanisms of AAA+ proteins involved in protein quality control.参与蛋白质质量控制的AAA+蛋白的共同和特定机制。
Biochem Soc Trans. 2008 Feb;36(Pt 1):120-5. doi: 10.1042/BST0360120.
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Characterization of an ERAD pathway for nonglycosylated BiP substrates, which require Herp.非糖基化结合免疫球蛋白重链结合蛋白（BiP）底物的内质网相关蛋白降解（ERAD）途径的特征分析，该途径需要Herp。
Mol Cell. 2007 Nov 30;28(4):544-54. doi: 10.1016/j.molcel.2007.09.012.
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A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum.一种基于脂质的用于在内质网中创建逃逸通道的模型。
Nature. 2007 Jul 26;448(7152):435-8. doi: 10.1038/nature06004.
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Characterization of the physiological turnover of native and inactivated cytochromes P450 3A in cultured rat hepatocytes: a role for the cytosolic AAA ATPase p97?培养大鼠肝细胞中天然和失活细胞色素P450 3A的生理周转特征：胞质AAA型ATP酶p97的作用？
Biochemistry. 2007 Jul 3;46(26):7793-803. doi: 10.1021/bi700340n. Epub 2007 Jun 6.
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Real-time fluorescence detection of ERAD substrate retrotranslocation in a mammalian in vitro system.在哺乳动物体外系统中对ERAD底物逆向转运进行实时荧光检测。
Cell. 2007 Jun 1;129(5):943-55. doi: 10.1016/j.cell.2007.03.046.
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SPFH2 mediates the endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors and other substrates in mammalian cells.SPFH2介导哺乳动物细胞中肌醇1,4,5-三磷酸受体及其他底物的内质网相关降解。
J Biol Chem. 2007 Jul 13;282(28):20104-15. doi: 10.1074/jbc.M701862200. Epub 2007 May 14.
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