Wallace Beth
Children's Hospital of Philadelphia, Clinical Nutrition, 34th and Civic Center Blvd, Philadelphia, PA 19104, USA.
Nutr Clin Pract. 2009 Feb-Mar;24(1):50-9. doi: 10.1177/0884533608329298.
Probiotics are live microorganisms that produce a benefit to the host when provided in adequate amounts from food or supplements. There is an increased interest in the use of probiotics in the management and treatment of complex medical conditions. Recommendations for probiotic supplementation in the pediatric population are often conflicting due to limited research in many pediatric disease states. Research on single and multistrain probiotics has shown promise for some pediatric populations. This review discusses the research available for probiotic supplementation for children with irritable bowel syndrome, Crohn's disease, diarrhea, short bowel syndrome, human immunodeficiency virus, and food allergies. Probiotic safety also is discussed.
益生菌是一类活的微生物，当从食物或补充剂中摄入足够量时，会给宿主带来益处。人们对在复杂医疗状况的管理和治疗中使用益生菌的兴趣日益增加。由于在许多儿科疾病状态下的研究有限，关于儿科人群补充益生菌的建议往往相互矛盾。对单一菌株和多菌株益生菌的研究已显示出对某些儿科人群的前景。本综述讨论了针对患有肠易激综合征、克罗恩病、腹泻、短肠综合征、人类免疫缺陷病毒和食物过敏的儿童补充益生菌的现有研究。还讨论了益生菌的安全性。
