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本文引用的文献

1
Dietary supplement intake by 6-month-old Taiwanese infants.6 个月大的台湾婴儿的膳食补充剂摄入量。
J Pediatr Gastroenterol Nutr. 2012 Jan;54(1):71-6. doi: 10.1097/MPG.0b013e31822dbafe.
2
Developing and refining the Taiwan Birth Cohort Study (TBCS): five years of experience.制定与完善台湾出生队列研究(TBCS):五年经验。
Res Dev Disabil. 2011 Nov-Dec;32(6):2697-703. doi: 10.1016/j.ridd.2011.06.002. Epub 2011 Jul 2.
3
Supplementation of infant formula with probiotics and/or prebiotics: a systematic review and comment by the ESPGHAN committee on nutrition.婴儿配方食品中添加益生菌和/或益生元:ESPGHAN 营养委员会的系统评价和评论。
J Pediatr Gastroenterol Nutr. 2011 Feb;52(2):238-50. doi: 10.1097/MPG.0b013e3181fb9e80.
4
Probiotics and prebiotics in pediatrics.儿科中的益生菌和益生元。
Pediatrics. 2010 Dec;126(6):1217-31. doi: 10.1542/peds.2010-2548. Epub 2010 Nov 29.
5
Probiotics for treating acute infectious diarrhoea.用于治疗急性感染性腹泻的益生菌
Cochrane Database Syst Rev. 2010 Nov 10;2010(11):CD003048. doi: 10.1002/14651858.CD003048.pub3.
6
Guidance for substantiating the evidence for beneficial effects of probiotics: prevention and management of allergic diseases by probiotics.益生菌有益作用证据的确证指南:益生菌预防和管理过敏性疾病。
J Nutr. 2010 Mar;140(3):713S-21S. doi: 10.3945/jn.109.113761. Epub 2010 Feb 3.
7
Guidance for substantiating the evidence for beneficial effects of probiotics: impact of probiotics on digestive system metabolism.益生菌有益作用证据的确证指南:益生菌对消化系统代谢的影响。
J Nutr. 2010 Mar;140(3):677S-89S. doi: 10.3945/jn.109.113738. Epub 2010 Jan 27.
8
Systematic review of randomised controlled trials: probiotics for functional constipation.系统评价随机对照试验:益生菌治疗功能性便秘。
World J Gastroenterol. 2010 Jan 7;16(1):69-75. doi: 10.3748/wjg.v16.i1.69.
9
Clinical use of probiotics in the pediatric population.益生菌在儿科人群中的临床应用。
Nutr Clin Pract. 2009 Feb-Mar;24(1):50-9. doi: 10.1177/0884533608329298.
10
Vitamin and mineral supplement use by children and adolescents in the 1999-2004 National Health and Nutrition Examination Survey: relationship with nutrition, food security, physical activity, and health care access.1999 - 2004年全国健康与营养检查调查中儿童及青少年使用维生素和矿物质补充剂的情况:与营养、食品安全、身体活动及医疗保健可及性的关系
Arch Pediatr Adolesc Med. 2009 Feb;163(2):150-7. doi: 10.1001/archpediatrics.2008.523.

台湾地区幼儿益生菌补充剂使用情况:一项前瞻性队列研究。

Probiotic supplement use among young children in Taiwan: a prospective cohort study.

机构信息

School of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan.

出版信息

PLoS One. 2012;7(9):e43885. doi: 10.1371/journal.pone.0043885. Epub 2012 Sep 12.

DOI:10.1371/journal.pone.0043885
PMID:22984450
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3440429/
Abstract

OBJECTIVES

The objective of this study is to provide details on probiotic supplement use among young children in Taiwan.

PARTICIPANTS AND METHODS

This study is based on the Taiwan Birth Cohort Study database. We used questionnaires to collect information on probiotic supplement use among young children from birth to 18 months of age, while also considering their demographic characteristics and other covariates. Low-birth-weight infants, preterm infants, those with birth defects, and those with caregivers who returned incomplete questionnaires were excluded. The final valid sample comprised 16,991 cases.

RESULTS

Approximately half the children received probiotic supplements before the age of 18 months. Only 6.3% of the children received probiotic supplements during the two periods of birth to 6 months and 7 to 18 months. Firstborn children, native mothers, mothers with higher educational levels, higher family income, and parents who lead healthy lifestyles were positively related to probiotic supplement use among children. Young children who were breastfed, with eczema, or with gastrointestinal tract problems were significantly positively associated with probiotic supplement use.

CONCLUSION

The findings show that probiotic supplement usage among young children is associated with a more socially advantaged circumstance and certain child health factors, such as eczema, diarrhea, and constipation. Parents might use probiotic supplements for prevention or treatment of child diseases. The findings of this research could serve as a baseline for future studies, and provide insight into probiotic supplement use behavior for health professionals caring for infants and young children.

摘要

目的

本研究旨在提供台湾地区婴幼儿益生菌补充剂使用情况的详细信息。

参与者和方法

本研究基于台湾出生队列研究数据库。我们使用问卷收集了 0-18 个月龄婴幼儿益生菌补充剂使用情况的信息,同时考虑了他们的人口统计学特征和其他协变量。排除了低出生体重儿、早产儿、出生缺陷儿和问卷回复不完整的照顾者。最终有效样本包括 16991 例。

结果

约一半的儿童在 18 个月前接受了益生菌补充剂。只有 6.3%的儿童在出生至 6 个月和 7 至 18 个月期间接受了益生菌补充剂。头胎、本地母亲、母亲受教育程度较高、家庭收入较高、父母生活方式健康的儿童更有可能使用益生菌补充剂。母乳喂养、患有湿疹或胃肠道问题的儿童使用益生菌补充剂的可能性显著增加。

结论

研究结果表明,婴幼儿益生菌补充剂的使用与更有利的社会环境和某些儿童健康因素有关,如湿疹、腹泻和便秘。父母可能会使用益生菌补充剂来预防或治疗儿童疾病。本研究的结果可以作为未来研究的基线,并为照顾婴儿和幼儿的健康专业人员提供有关益生菌补充剂使用行为的见解。