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Carcinogenic and mutagenic activities of safrole, 1'-hydroxysafrole, and some known or possible metabolites.

作者信息

Wislocki P G, Miller E C, Miller J A, McCoy E C, Rosenkranz H S

出版信息

Cancer Res. 1977 Jun;37(6):1883-91.

PMID:192464
Abstract
摘要

相似文献

1
Carcinogenic and mutagenic activities of safrole, 1'-hydroxysafrole, and some known or possible metabolites.
Cancer Res. 1977 Jun;37(6):1883-91.
2
1'-Hydroxysafrole, a proximate carcinogenic metabolite of safrole in the rat and mouse.
Cancer Res. 1973 Mar;33(3):590-600.
3
[Mutagenicity of the metabolites of the epoxide-diol pathway of safrole and its analogs. Study on Salmonella typhimurium].黄樟素及其类似物环氧化物-二醇途径代谢产物的致突变性。鼠伤寒沙门氏菌研究
C R Seances Soc Biol Fil. 1977;171(5):1041-8.
4
Structure-activity studies of the carcinogenicities in the mouse and rat of some naturally occurring and synthetic alkenylbenzene derivatives related to safrole and estragole.一些与黄樟素和草蒿脑相关的天然存在及合成的烯基苯衍生物在小鼠和大鼠体内致癌性的构效关系研究。
Cancer Res. 1983 Mar;43(3):1124-34.
5
Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver.对短尾小鼠和五氯苯酚的研究提供了有力证据，表明1'-磺氧基黄樟素是1'-羟基黄樟素在小鼠肝脏中的主要最终亲电致癌代谢产物。
Cancer Res. 1983 Nov;43(11):5163-73.
6
Safrole, isosafrole and dihydrosafrole.黄樟素、异黄樟素和二氢黄樟素。
IARC Monogr Eval Carcinog Risk Chem Man. 1976;10:231-44.
7
The metabolic activation of the carcinogen 1'-hydroxysafrole in vivo and in vitro and the electrophilic reactivities of possible ultimate carcinogens.
Cancer Res. 1976 May;36(5):1686-95.
8
Vinyl carbamate as a promutagen and a more carcinogenic analog of ethyl carbamate.氨基甲酸乙烯酯作为一种前诱变剂以及氨基甲酸乙酯的一种更具致癌性的类似物。
Cancer Res. 1978 Nov;38(11 Pt 1):3793-804.
9
[A new animal for experimental oncologic research--the Dzhungarian hamster].
Vopr Onkol. 1970;16(3):90-8.
10
Sulfuric acid esters as ultimate electrophilic and carcinogenic metabolites of some alkenylbenzenes and aromatic amines in mouse liver.硫酸酯作为某些链烯基苯和芳香胺在小鼠肝脏中的最终亲电和致癌代谢产物。
Carcinog Compr Surv. 1985;10:93-107.

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J Toxicol Pathol. 2013 Mar;26(1):19-27. doi: 10.1293/tox.26.19. Epub 2013 Apr 22.
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Use of physiologically based biokinetic (PBBK) modeling to study estragole bioactivation and detoxification in humans as compared with male rats.与雄性大鼠相比，使用基于生理学的生物动力学（PBBK）模型研究人类中草蒿脑的生物活化和解毒作用。
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