Mayer-Davis Elizabeth J, Beyer Jennifer, Bell Ronny A, Dabelea Dana, D'Agostino Ralph, Imperatore Giuseppina, Lawrence Jean M, Liese Angela D, Liu Lenna, Marcovina Santica, Rodriguez Beatriz
Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Diabetes Care. 2009 Mar;32 Suppl 2(Suppl 2):S112-22. doi: 10.2337/dc09-S203.
To report the prevalence and incidence of type 1 and type 2 diabetes among African American youth and to describe demographic, clinical, and behavioral characteristics.
Data from the SEARCH for Diabetes in Youth Study, a population-based, multicenter observational study of youth with clinically diagnosed diabetes aged 0-19 years, were used to estimate the prevalence for calendar year 2001 (692 cases) and incidence based on 748 African American case subjects diagnosed in 2002-2005. Characteristics of these youth were obtained during a research visit for 436 African American youth with type 1 diabetes and 212 African American youth with type 2 diabetes.
Among African American youth aged 0-9 years, prevalence (per 1,000) of type 1 diabetes was 0.57 (95% CI 0.47-0.69) and for those aged 10-19 years 2.04 (1.85-2.26). Among African American youth aged 0-9 years, annual type 1 diabetes incidence (per 100,000) was 15.7 (13.7-17.9) and for those aged 10-19 years 15.7 (13.8-17.8). A1C was >or=9.5% among 50% of youth with type 1 diabetes aged >or=15 years. Across age-groups and sex, 44.7% of African American youth with type 1 diabetes were overweight or obese. Among African American youth aged 10-19 years, prevalence (per 1,000) of type 2 diabetes was 1.06 (0.93-1.22) and annual incidence (per 100,000) was 19.0 (16.9-21.3). About 60% of African American youth with type 2 diabetes had an annual household income of <$25,000. Among those aged >or=15 years, 27.5% had an A1C >or=9.5%, 22.5% had high blood pressure, and, across subgroups of age and sex, >90% were overweight or obese.
Type 1 diabetes presents a serious burden among African American youth aged <10 years, and African American adolescents are impacted substantially by both type 1 and type 2 diabetes.
报告非裔美国青少年1型和2型糖尿病的患病率及发病率，并描述其人口统计学、临床和行为特征。
青少年糖尿病SEARCH研究的数据，一项基于人群的多中心观察性研究，研究对象为0至19岁临床诊断为糖尿病的青少年，用于估计2001年的患病率（692例）以及基于2002 - 2005年确诊的748例非裔美国病例受试者的发病率。这些青少年的特征是在对436例1型糖尿病非裔美国青少年和212例2型糖尿病非裔美国青少年的研究访视期间获得的。
在0至9岁的非裔美国青少年中，1型糖尿病的患病率（每1000人）为0.57（95%CI 0.47 - 0.69），10至19岁的患病率为2.04（1.85 - 2.26）。在0至9岁的非裔美国青少年中，1型糖尿病的年发病率（每100,000人）为15.7（13.7 - 17.9），10至19岁的发病率为15.7（13.8 - 17.8）。在15岁及以上的1型糖尿病青少年中，50%的糖化血红蛋白（A1C）≥9.5%。在各年龄组和性别中，44.7%的1型糖尿病非裔美国青少年超重或肥胖。在10至19岁的非裔美国青少年中，2型糖尿病的患病率（每1000人）为1.06（0.93 - 1.22），年发病率（每100,000人）为19.0（16.9 - 21.3）。约60%的2型糖尿病非裔美国青少年家庭年收入低于25,000美元。在15岁及以上的人群中，27.5%的糖化血红蛋白≥9.5%，22.5%患有高血压，在各年龄和性别的亚组中，超过90%超重或肥胖。
1型糖尿病给10岁以下的非裔美国青少年带来了沉重负担，非裔美国青少年受到1型和2型糖尿病的严重影响。
