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Cellular and molecular changes in mammary epithelial cells following irradiation.

作者信息

Ullrich R L

机构信息

Department of Radiation Therapy, University of Texas Medical Branch, Galveston 77550.

出版信息

Radiat Res. 1991 Oct;128(1 Suppl):S136-40.

PMID:1924740
Abstract

The present paper describes experiments conducted over the last several years which have focused primarily on the development of mammary tumors in BALB/c mice after neutron and gamma irradiation. Time-dose relationships for induction of mammary and lung tumors following irradiation with fission-spectrum neutrons and 137Cs gamma rays are described. Subsequent studies have used in vivo/in vitro approaches to characterize cellular and molecular changes. These studies suggest quantitative and qualitative differences in the effects of neutrons and gamma rays.

摘要

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