Wagai John, Senga John, Fegan Greg, English Mike
Child and Newborn Health Group, Centre for Geographic Medicine, Kenyan Medical Research Institute-Wellcome Trust Programme, Nairobi, Kenya.
PLoS One. 2009;4(2):e4626. doi: 10.1371/journal.pone.0004626. Epub 2009 Feb 27.
Case management guidelines use a limited set of clinical features to guide assessment and treatment for common childhood diseases in poor countries. Using video records of clinical signs we assessed agreement among experts and assessed whether Kenyan health workers could identify signs defined by expert consensus.
104 videos representing 11 clinical sign categories were presented to experts using a web questionnaire. Proportionate agreement and agreement beyond chance were calculated using kappa and the AC1 statistic. 31 videos were selected and presented to local health workers, 20 for which experts had demonstrated clear agreement and 11 for which experts could not demonstrate agreement.
Experts reached very high level of chance adjusted agreement for some videos while for a few videos no agreement beyond chance was found. Where experts agreed Kenyan hospital staff of all cadres recognised signs with high mean sensitivity and specificity (sensitivity: 0.897-0.975, specificity: 0.813-0.894); years of experience, gender and hospital had no influence on mean sensitivity or specificity. Local health workers did not agree on videos where experts had low or no agreement. Results of different agreement statistics for multiple observers, the AC1 and Fleiss' kappa, differ across the range of proportionate agreement.
Videos provide a useful means to test agreement amongst geographically diverse groups of health workers. Kenyan health workers are in agreement with experts where clinical signs are clear-cut supporting the potential value of assessment and management guidelines. However, clinical signs are not always clear-cut. Video recordings offer one means to help standardise interpretation of clinical signs.
病例管理指南使用有限的一系列临床特征来指导贫困国家常见儿童疾病的评估和治疗。我们利用临床体征的视频记录评估了专家之间的一致性,并评估了肯尼亚卫生工作者是否能够识别专家共识所定义的体征。
通过网络问卷向专家展示了代表11种临床体征类别的104个视频。使用kappa和AC1统计量计算了比例一致性和超出机遇的一致性。选择了31个视频展示给当地卫生工作者,其中20个视频专家已表明有明确的一致性,11个视频专家未表明有一致性。
对于一些视频,专家们达成了非常高的机遇调整一致性水平,而对于少数视频,未发现超出机遇的一致性。在专家达成一致的地方,肯尼亚各级医院工作人员识别体征的平均敏感性和特异性都很高(敏感性:0.897 - 0.975,特异性:0.813 - 0.894);工作年限、性别和医院对平均敏感性或特异性没有影响。在专家一致性较低或无一致性的视频上,当地卫生工作者意见不一。多个观察者的不同一致性统计结果,即AC1和Fleiss' kappa,在比例一致性范围内有所不同。
视频为测试不同地理位置的卫生工作者群体之间的一致性提供了一种有用的方法。在临床体征明确的情况下,肯尼亚卫生工作者与专家意见一致,这支持了评估和管理指南的潜在价值。然而,临床体征并非总是明确的。视频记录提供了一种帮助标准化临床体征解释的方法。