Fukamizu Koji, Miyake Yoshihiro, Nishibayashi Yoshiaki
Institute of Engineering Innovation, School of Engineering, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo, 113-8656, Japan.
Angew Chem Int Ed Engl. 2009;48(14):2534-7. doi: 10.1002/anie.200900392.
Another way to dienes: The ruthenium-catalyzed 6-endo-cycloisomerization of 1,5-enynes gives the corresponding 1,3-cyclohexadienes in high to excellent yields. This novel synthetic and catalytic method constitutes another way to selectively prepare 1,3-cyclohexadienes, this cyclic diene skeleton being a core subunit in many natural products and a useful building block for a variety of organic transformations.
钌催化的1,5-烯炔的6-内型环异构化反应能以高至优异的产率得到相应的1,3-环己二烯。这种新颖的合成与催化方法构成了另一种选择性制备1,3-环己二烯的途径，这种环状二烯骨架是许多天然产物的核心亚基，也是各种有机转化反应中有用的结构单元。
