Avritscher Rony, Gupta Sanjay
Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 325, Houston, TX 77030, USA.
Hematol Oncol Clin North Am. 2009 Feb;23(1):129-37, ix. doi: 10.1016/j.hoc.2008.11.002.
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasm of the gastrointestinal tract. The interventional radiologist plays an important role in the diagnosis and locoregional therapy for metastatic GISTs. Radiofrequency ablation (RFA) is a potentially curative option for patients exhibiting partial response to imatinib with focal residual disease. RFA can also be used for local control of focal hepatic or peritoneal metastasis. Hepatic embolization or chemoembolization is reserved for the treatment of progressive liver disease in imatinib-resistant patients who are not suitable for sunitinib as a second-line therapy.
胃肠道间质瘤（GISTs）是胃肠道最常见的间叶性肿瘤。介入放射科医生在转移性GISTs的诊断和局部区域治疗中发挥着重要作用。对于对伊马替尼有部分反应且有局灶性残留病灶的患者，射频消融（RFA）是一种潜在的治愈性选择。RFA也可用于局部控制局灶性肝转移或腹膜转移。肝栓塞或化疗栓塞则用于治疗对伊马替尼耐药且不适合使用舒尼替尼作为二线治疗的进展性肝病患者。
