Völkl-Kernstock Sabine, Bauch-Prater Sonja, Ponocny-Seliger Elisabeth, Feucht Martha
Department of Psychiatry for Children and Adolescents, Medical University Vienna, Austria.
Seizure. 2009 Jun;18(5):320-6. doi: 10.1016/j.seizure.2008.11.011. Epub 2009 Feb 26.
To assess prospectively language and speech ability in children with benign partial epilepsy with centro-temporal spikes (BCECTS). To evaluate academic performance and social competencies both during the active disease and after remission.
Right-handed school children with typical BCECTS and a control group matched by age, sex, handedness and socioeconomic status were examined. The German version of WISC-R, the "Tübinger Luria Christensen Neuropsychological Test Set for children" (TUKI), the "Verbal Learning Memory Test" (VLMT), the "Heidelberger Speech Development Test-second edition" (HSET), and the "Salzburger reading and writing test" (SLRT) were applied. The Child Behavior Checklist (CBCL) and a semi-structured interview were performed with the children's teachers to gain insight into school performance, behavioral and emotional problems.
During the active phase, the patient group - despite normal global intellectual abilities - showed few, but significant impairments both in expressive speech and in receptive and expressive vocabulary. A significant deficit in the ability to recognize and express interpersonal relations was also found. Patients' teachers stated deficits concerning academic performance and complained about disturbing behavior. Parents reported significantly more psycho-pathological features in the subscales "Aggressive Behavior", "Attention Problems" and "Anxious/Depressed" of the CBCL. Results were independent of medication and spike localization. After complete recovery from BCECTS, these problems were not found any more.
Both deficits of speech-related abilities (in both expressive and receptive vocabulary) and behavioral disturbances can be detected in children with typical BCECTS, but are no longer apparent after remission of the seizure disorder.
前瞻性评估伴有中央颞区棘波的儿童良性部分性癫痫（BCECTS）患儿的语言和言语能力。评估疾病活动期及缓解期后的学业成绩和社交能力。
对患有典型BCECTS的右利手学龄儿童以及按年龄、性别、利手和社会经济地位匹配的对照组进行检查。应用了WISC-R德文版、“儿童图宾根卢里亚·克里斯滕森神经心理测试集”（TUKI）；“言语学习记忆测试”（VLMT）、“海德堡言语发展测试第二版”（HSET）以及“萨尔茨堡读写测试”（SLRT）。对儿童的教师进行儿童行为量表（CBCL）和半结构化访谈，以深入了解学业表现、行为和情绪问题。
在疾病活动期，尽管患者组整体智力正常，但在表达性言语以及接受性和表达性词汇方面均表现出轻微但显著的损伤。还发现了在识别和表达人际关系能力方面存在显著缺陷。患者的教师指出其学业成绩存在缺陷，并抱怨其行为令人困扰。家长报告称，在CBCL的“攻击性行为”、“注意力问题”和“焦虑/抑郁”分量表中，心理病理特征明显更多。结果与药物治疗和棘波定位无关！BCECTS完全恢复后，这些问题不再出现。
在患有典型BCECTS的儿童中，可检测到与言语相关能力的缺陷（包括表达性和接受性词汇）以及行为障碍，但在癫痫发作障碍缓解后不再明显。
