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锂和运动对大鼠血清铜和锌水平的影响。

Influence of lithium and exercise on serum levels of copper and zinc in rats.

作者信息

Córdova A, Escanero J F

机构信息

Departamento de Fisiología, Colegio Universitario de Soria, Universidad de Valladolid, Soria, Spain.

出版信息

Rev Esp Fisiol. 1991 Jun;47(2):87-90.

PMID:1924968
Abstract

The variations in serum levels of Cu and Zn induced by exercise in rats undergoing Li therapy are determined. The results show that exercise until exhaustion leads to a reduction in the Li concentration, which is more pronounced in rats subjected to training (to 50% maximum capacity) in the week before the test. The serum levels of Zn and Cu increased significantly with exhaustion in untrained rats, while there were no significant alterations in trained rats, except for serum Zn in those not treated with Li. The modifications in serum induced by exhaustion are lower in rats treated with Li. It is likely that Li and exercise have opposite effects on the tissue distribution of the two ions studied.

摘要

测定了接受锂治疗的大鼠运动后血清中铜和锌水平的变化。结果表明,运动至力竭会导致锂浓度降低,在测试前一周接受训练(达到最大能力的50%)的大鼠中这种降低更为明显。未训练的大鼠力竭时血清锌和铜水平显著升高,而训练过的大鼠除未接受锂治疗的大鼠血清锌外无显著变化。锂治疗的大鼠力竭引起的血清变化较小。锂和运动可能对所研究的两种离子的组织分布有相反的影响。

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