Alaoui A Y, Ouzidane L, Sqalli S, el Meziane A, Naciri A, Bartal M
Service de Pneumologie, Centre Hospitalier Universitaire Ibnou Rochd, Casablanca, Maroc.
Rev Mal Respir. 1991;8(4):403-6.
Non Hodgkin's lymphoma (LNH) presenting as a localised tumour is exceptional and nearly always appears during the course of disseminated disease. We report a case where the primary disease was an endobronchial tumour and the entire clinical picture related to pulmonary symptoms. A 70 year old lady was found to have a left sided pulmonary opacity following a cough with minimal expectoration and accompanied by chest pains and dyspnoea. The chest abnormality progressed for 3 years 9 months before an endobronchial tumour was discovered at bronchoscopy in the left upper lobe and from which a biopsy revealed an LNH with small cells of low degree of malignancy. In addition there was splenomegaly and an infiltration of bone marrow by the lymphomatous process which was evidence of a disseminated form of LNH. To our knowledge our observation is an extremely rare case where an endobronchial tumour revealed a non Hodgkins lymphoma.
以局限性肿瘤形式出现的非霍奇金淋巴瘤(LNH)极为罕见,几乎总是在疾病播散过程中出现。我们报告一例,其原发疾病为支气管内肿瘤,整个临床症状均与肺部症状相关。一名70岁女性,咳嗽伴少量咳痰,并伴有胸痛和呼吸困难,胸部X光检查发现左侧肺部有阴影。胸部异常情况持续了3年9个月,之后在支气管镜检查时发现左上叶有一个支气管内肿瘤,活检显示为低度恶性的小细胞LNH。此外,还存在脾肿大以及淋巴瘤对骨髓的浸润,这是LNH播散形式的证据。据我们所知,我们观察到的是极为罕见的由支气管内肿瘤发现非霍奇金淋巴瘤的病例。