Foster M, Fell L, Pocklington T, Akinsete F, Dawson A, Hutchison J M, Mallard J R
Clin Radiol. 1977 Jan;28(1):15-22. doi: 10.1016/s0009-9260(77)80130-x.
Electron spin resonance spectroscopy has proved a useful and simple technique for the measurement of levels of caeruloplasmin and iron transferrin in whole blood from 50 patients with Hodgkin's disease. Those patients with clinically active disease show higher caeruloplasmin levels and lower iron transferrin levels than those with inactive disease. The results indicate that these tests are good indicators of the state of the disease and that serial measurement of these parameters may help in early prediction of clinical reactivity and in monitoring response to treatment. The combined information from iron transferrin and caeruloplasmin levels appears to be more predictive than that from the erythrocyte sedimentation rate and neutrophil alkaline phosphatase score.
电子自旋共振光谱法已被证明是一种有用且简单的技术,可用于测量50例霍奇金病患者全血中的铜蓝蛋白和转铁蛋白水平。与病情不活跃的患者相比,临床病情活跃的患者铜蓝蛋白水平较高,转铁蛋白水平较低。结果表明,这些检测是疾病状态的良好指标,对这些参数进行连续测量可能有助于早期预测临床反应性以及监测治疗反应。转铁蛋白和铜蓝蛋白水平的综合信息似乎比红细胞沉降率和中性粒细胞碱性磷酸酶评分更具预测性。