2型糖尿病患者使用地特胰岛素时更高的剂量需求——三例病例及文献综述
Higher dose requirements with insulin detemir in type 2 diabetes--three cases and a review of the literature.
作者信息
Swinnen Sanne G H A, DeVries J Hans
机构信息
Department of Internal Medicine, Academic Medical Centre, Amsterdam, The Netherlands.
出版信息
Diabetes Res Clin Pract. 2009 May;84(2):e24-6. doi: 10.1016/j.diabres.2009.02.009. Epub 2009 Feb 28.
Abstract
We report on three type 2 diabetic patients whose daily basal insulin dose requirements were substantially reduced after switching from insulin detemir to insulin glargine. Meta-analysis of three randomised trials of basal insulin initiation confirmed this increased insulin detemir dose requirement in type 2 patients. Potential explanations are discussed.
摘要
我们报告了三名2型糖尿病患者，他们从地特胰岛素转换为甘精胰岛素后，每日基础胰岛素剂量需求大幅降低。三项基础胰岛素起始治疗随机试验的荟萃分析证实，2型患者中地特胰岛素的剂量需求增加。文中讨论了可能的解释。
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