Papadopoulos Vassilis G, Kourea Helen P, Adonakis George L, Decavalas George O
Department of Obstetrics and Gynaecology, Patras University Hospital, Greece.
Eur J Obstet Gynecol Reprod Biol. 2009 May;144(1):8-14. doi: 10.1016/j.ejogrb.2009.01.011. Epub 2009 Feb 28.
Hemangiomas of the umbilical cord are extremely rare benign vascular tumors, not always detected prenatally. They have been associated with increased alpha-fetoprotein (AFP), hydramnios, congenital anomalies, and increased perinatal mortality. Impaired umbilical circulation has been proposed as the predisposing factor for fetal compromise. We report a case of an antenatally detected umbilical cord hemangioma with one artery crossing the tumor, and we reviewed the literature. Close surveillance with Doppler flow studies of the umbilical vessels were carried out throughout the pregnancy. All indices were normal, except from the intra-tumoral part of the umbilical artery under discussion that showed increasing resistance from 32 weeks onwards. Our review confirmed the reported association with increased AFP and hydramnios. The placental end of the cord was the preferred site of location, and the umbilical artery the commonest vessel of origin. Association with cutaneous vascular malformations, and single umbilical artery were assessed.
脐带血管瘤是极其罕见的良性血管肿瘤，并非总能在产前检测到。它们与甲胎蛋白（AFP）升高、羊水过多、先天性异常及围产期死亡率增加有关。有人提出脐带循环受损是导致胎儿窘迫的诱发因素。我们报告一例产前检测到的脐带血管瘤病例，有一条动脉穿过肿瘤，并对相关文献进行了回顾。整个孕期对脐血管进行了多普勒血流研究密切监测。除了所讨论的脐动脉肿瘤内部分从32周起阻力增加外，所有指标均正常。我们的回顾证实了与AFP升高和羊水过多的报道关联。脐带的胎盘端是首选的发病部位，脐动脉是最常见的起源血管。评估了与皮肤血管畸形和单脐动脉的关联。
