Dangoisse C, Ledoux M
Clinique Dermatologique, Hôpitaux universitaire Saint-Pierre.
Rev Med Brux. 1991 Sep;12(7):257-66.
Pressure is the primary pathogenic factor in the development of ulcers but other major factors are shearing forces, friction and moisture. Significant risk factors are immobility, nutritional status and age-related diseases. Complications of pressure ulcers can be life threatening. The authors wish to stress preventive measures and also recommend a therapeutic approach based on the grade of ulcer present. Prevention is best achieved by identification of high risk patients, alleviation of causative and predisposing factors and early detection of ischemic skin changes. The treatment includes local wound care that eliminates necrotic tissue, decreases bacterial load and provides a physiologic environment allowing the wound to heal, and systemic treatment: adequate nutrition, correction of underlying illnesses and systemic antibiotics (in case of sepsis, cellulitis, osteomyelitis or the prevention of bacterial endocarditis).
压力是溃疡形成的主要致病因素,但其他主要因素包括剪切力、摩擦和潮湿。重要的危险因素有活动受限、营养状况及与年龄相关的疾病。压疮的并发症可能危及生命。作者希望强调预防措施,并根据现有溃疡的分级推荐一种治疗方法。通过识别高危患者、减轻致病和诱发因素以及早期发现缺血性皮肤变化,能最好地实现预防。治疗包括局部伤口护理,即清除坏死组织、降低细菌载量并提供有利于伤口愈合的生理环境,以及全身治疗:充足的营养、治疗基础疾病和使用全身抗生素(用于败血症、蜂窝织炎、骨髓炎或预防细菌性心内膜炎的情况)。