Alvarez O M, Childs E J
University Wound Healing Clinic, New Brunswick, New Jersey.
Clin Podiatr Med Surg. 1991 Oct;8(4):869-90.
Pressure ulcers are a common and serious problem predominately among elderly persons who are confined to bed or chair. Additional factors associated with pressure ulcer development include cerebrovascular accident, impaired nutritional intake, urinary or fecal incontinence, hypoalbuminemia, and previous fracture. Implementation of preventive measures, such as an in-depth assessment for mobility, a pressure-relieving device combined with adequate repositioning, and thorough evaluation for nutritional status and urinary incontinence, significantly reduce pressure ulcer incidence. If the pressure ulcer is a partial thickness (stage II) wound, the causative factors are probably friction or moisture. If the ulcer is full thickness (stage III and IV), it is secondary to pressure or shearing forces. The development of wound infection is the most common complication in the management approach. Osteomyelitis is not an uncommon occurrence and must be initially ruled out in all full thickness pressure ulcers. Surgical debridement of necrotic tissue is necessary prior to further treatment and assessments. Antibiotic therapy is indicated only upon evidence of infection (cellulitis, osteomyelitis, leukocytosis, bandemia, or fever). Topical pharmacologic agents may be used to prevent or treat infection but must be carefully controlled to avoid such adverse effects as toxicity to the wound, allergic reaction, and development of resistant pathogens. Proper use of occlusive dressings increase patient comfort, enhance healing, decrease the possibility of infection, save time, and reduce costs. A patient presenting an ulcer that fails to improve or, because of its size, will take a great deal of time to heal should be evaluated for surgical closure.
压疮是一个常见且严重的问题,主要发生在卧床或坐轮椅的老年人中。与压疮形成相关的其他因素包括脑血管意外、营养摄入受损、大小便失禁、低白蛋白血症和既往骨折。实施预防措施,如对活动能力进行深入评估、使用减压装置并结合适当的翻身,以及对营养状况和尿失禁进行全面评估,可显著降低压疮发生率。如果压疮是部分厚度(Ⅱ期)伤口,其致病因素可能是摩擦或潮湿。如果溃疡是全层厚度(Ⅲ期和Ⅳ期),则继发于压力或剪切力。伤口感染的发生是治疗过程中最常见的并发症。骨髓炎并不罕见,在所有全层厚度压疮中都必须首先排除。在进一步治疗和评估之前,有必要对坏死组织进行手术清创。仅在有感染证据(蜂窝织炎、骨髓炎、白细胞增多、杆状核细胞增多或发热)时才使用抗生素治疗。局部用药可用于预防或治疗感染,但必须谨慎控制,以避免对伤口产生毒性、过敏反应和耐药病原体形成等不良反应。正确使用封闭敷料可提高患者舒适度、促进愈合、降低感染可能性、节省时间并降低成本。对于溃疡未改善或因面积较大需要很长时间才能愈合的患者,应评估是否适合手术闭合。