• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Drug oxidations dependent on cytochrome P-450 in isolated hepatocytes. The role of the tricarboxylates and the aminotransferases in NADPH supply.

作者信息

Weigl K, Sies H

出版信息

Eur J Biochem. 1977 Jul 15;77(2):401-8. doi: 10.1111/j.1432-1033.1977.tb11680.x.

DOI:10.1111/j.1432-1033.1977.tb11680.x
PMID:19252
Abstract
摘要

相似文献

1
Drug oxidations dependent on cytochrome P-450 in isolated hepatocytes. The role of the tricarboxylates and the aminotransferases in NADPH supply.分离肝细胞中依赖细胞色素P - 450的药物氧化作用。三羧酸和氨基转移酶在烟酰胺腺嘌呤二核苷酸磷酸(NADPH)供应中的作用。
Eur J Biochem. 1977 Jul 15;77(2):401-8. doi: 10.1111/j.1432-1033.1977.tb11680.x.
2
The mitochondrial role in hepatic cell mixed-function oxidations.
Ann N Y Acad Sci. 1973;212:420-7. doi: 10.1111/j.1749-6632.1973.tb47611.x.
3
Hepatic calcium efflux during cytochrome P-450-dependent drug oxidations at the endoplasmic reticulum in intact liver.完整肝脏内质网中细胞色素P-450依赖的药物氧化过程中的肝脏钙外流。
Proc Natl Acad Sci U S A. 1981 Jun;78(6):3358-62. doi: 10.1073/pnas.78.6.3358.
4
Acute toxicity of substrates of the mixed function oxidase system in normal and phenobarbital-pretreated mice.混合功能氧化酶系统底物在正常及苯巴比妥预处理小鼠中的急性毒性
J Toxicol Environ Health. 1975 Sep;1(1):39-46. doi: 10.1080/15287397509529307.
5
Effects of Triton X-100 on drug hydroxylation system of rat liver microsomes induced by phenobarbital or 3-methylcholanthrene.曲拉通X-100对苯巴比妥或3-甲基胆蒽诱导的大鼠肝微粒体药物羟化系统的影响。
J Biochem. 1972 Dec;72(6):1361-7. doi: 10.1093/oxfordjournals.jbchem.a130029.
6
Instability of mixed function monooxygenases in frozen rat liver.冷冻大鼠肝脏中混合功能单加氧酶的不稳定性
Res Commun Chem Pathol Pharmacol. 1976 Jun;14(2):295-303.
7
Oxidation-reduction states of pyridine nucleotide and cytochrome P-450 during mixed-function oxidation in perfused rat liver.灌注大鼠肝脏混合功能氧化过程中吡啶核苷酸和细胞色素P-450的氧化还原状态
J Biol Chem. 1981 Dec 25;256(24):12933-9.
8
[Permeability of rat liver mitochondria to mitochondrial aspartate aminotransferase. II. Effect of cycloserine and aminooxyacetate on changes in the rate of oxidation of intramitochondrial NAD(P)H induced by the addition of mAAT].
Boll Soc Ital Biol Sper. 1976 Sep 15;52(17):1356-60.
9
Vinyl chloride-induced deactivation of cytochrome P-450 and other components of the liver mixed function oxidase system: an in vivo study.氯乙烯对细胞色素P - 450及肝脏混合功能氧化酶系统其他组分的失活作用:一项体内研究。
Res Commun Chem Pathol Pharmacol. 1975 Dec;12(4):685-94.
10
Induction of liver microsomal drug metabolism in newly-hatched chicks.新孵化雏鸡肝脏微粒体药物代谢的诱导
Br J Pharmacol. 1973 Mar;47(3):624P-625P.

引用本文的文献

1
Redox pioneer: professor Helmut Sies.氧化还原领域先驱:赫尔穆特·西尔斯教授。
Antioxid Redox Signal. 2014 Dec 20;21(18):2459-68. doi: 10.1089/ars.2014.6037. Epub 2014 Oct 9.
2
Glucose regulation of hydroperoxide metabolism in rat intestinal cells. Stimulation of reduced nicotinamide adenine dinucleotide phosphate supply.大鼠肠道细胞中过氧化氢代谢的葡萄糖调节。还原型烟酰胺腺嘌呤二核苷酸磷酸供应的刺激。
J Clin Invest. 1994 Dec;94(6):2426-34. doi: 10.1172/JCI117610.
3
NADP-dependent dehydrogenases in rat liver parenchyma. III. The description of a liponeogenic area on the basis of histochemically demonstrated enzyme activities and the neutral fat content during fasting and refeeding.
大鼠肝实质中的NADP依赖性脱氢酶。III. 根据组织化学显示的酶活性及禁食和再喂食期间的中性脂肪含量对一个脂肪生成区域的描述。
Histochemistry. 1981;72(4):579-615. doi: 10.1007/BF00493277.
4
Corticosterone catabolism by mouse liver homogenate: strain difference in dependence on added NADP.小鼠肝脏匀浆对皮质酮的分解代谢:添加烟酰胺腺嘌呤二核苷酸磷酸(NADP)时的品系差异
J Endocrinol Invest. 1981 Apr-Jun;4(2):193-6. doi: 10.1007/BF03350451.
5
Further evidence for the participation of 5 beta-steroids in the development of a porphyria induced by hexachlorobenzene.关于5β-类固醇参与六氯苯诱导的卟啉症发展的进一步证据。
Arch Toxicol. 1982 Sep;50(3-4):233-9. doi: 10.1007/BF00310855.
6
Involvement of glutathione reductase in selenite metabolism and toxicity, studied in isolated rat hepatocytes.谷胱甘肽还原酶在亚硒酸盐代谢及毒性中的作用,以分离的大鼠肝细胞为研究对象。
Arch Toxicol. 1982 Jul;50(2):113-23. doi: 10.1007/BF00373393.
7
Hepatic calcium efflux during cytochrome P-450-dependent drug oxidations at the endoplasmic reticulum in intact liver.完整肝脏内质网中细胞色素P-450依赖的药物氧化过程中的肝脏钙外流。
Proc Natl Acad Sci U S A. 1981 Jun;78(6):3358-62. doi: 10.1073/pnas.78.6.3358.
8
Physiological roles of nicotinamide nucleotide transhydrogenase.烟酰胺核苷酸转氢酶的生理作用。
Biochem J. 1988 Aug 15;254(1):1-10. doi: 10.1042/bj2540001.