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[抗惊厥治疗开始前及停止时脑电图的预后价值]

[Prognostic value of the EEG prior to the start and the discontinuation of anticonvulsive therapy].

作者信息

Donati F, Vassella F, Pavlincova E

机构信息

Abteilung für Kinderneurologie, Medizinische Universitätsklinik, Inselspital Bern.

出版信息

Schweiz Rundsch Med Prax. 1991 Sep 3;80(36):919-21.

PMID:1925208
Abstract

Opinions are divided about the prognostic value of the EEG in the course of epilepsy. We thus prospectively examined 275 children with epilepsy; in particular, we analyzed the prognostic role of the EEG. Out of these 275 children 209 (76%) have been free from attacks for more than one year. In 107 children the anticonvulsive therapy was discontinued, leading to a relapse rate of 27%. According to our results, only the focal EEG changes, up to interruption of the anticonvulsive therapy, show a statistical significance in the course of epilepsy. On the other hand, a normal EEG before or normalization of the EEG after commencement of therapy and also the absence of any epileptic activity (focal or generalized), are likely to be favourable. However, we could not find a statistically significant difference.

摘要

关于脑电图(EEG)在癫痫病程中的预后价值,观点存在分歧。因此,我们对275例癫痫患儿进行了前瞻性研究;特别地,我们分析了脑电图的预后作用。在这275例患儿中,209例(76%)已无发作超过一年。107例患儿停用抗惊厥治疗,复发率为27%。根据我们的结果,仅局灶性脑电图改变,直至抗惊厥治疗中断,在癫痫病程中具有统计学意义。另一方面,治疗开始前脑电图正常或治疗后脑电图恢复正常,以及无任何癫痫活动(局灶性或全身性),可能是有利的。然而,我们未发现统计学上的显著差异。

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