一家三级医疗机构中梭菌血症的流行病学及转归
Epidemiology and outcomes of clostridial bacteremia at a tertiary-care institution.
作者信息
Shah Monica, Bishburg Eliahu, Baran David A, Chan Trini
机构信息
Newark Beth Israel Medical Center, Newark, NJ, USA.
出版信息
ScientificWorldJournal. 2009 Feb 28;9:144-8. doi: 10.1100/tsw.2009.21.
Abstract
A review was performed to determine the epidemiology and outcomes of clostridial bacteremia (CB) at our institution. Ninety-two percent of patients had monomicrobial CB. Patients with Clostridium innocuum bacteremia had a significantly higher 2-day mortality rate compared to patients with C. septicum and C. perfringens. CB is associated with high and rapid mortality, especially in patients with malignancy. Early mortality was significantly lower in patients receiving antibiotics with adequate coverage for Clostridium species.
摘要
我们进行了一项回顾性研究，以确定我院梭状芽孢杆菌血症（CB）的流行病学情况和治疗结果。92%的患者为单一微生物引起的CB。与败毒梭状芽孢杆菌和产气荚膜梭菌感染的患者相比，无害梭状芽孢杆菌血症患者的2天死亡率显著更高。CB与高死亡率和快速死亡相关，尤其是在恶性肿瘤患者中。接受对梭状芽孢杆菌有足够覆盖范围抗生素治疗的患者早期死亡率显著更低。
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