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前庭性偏头痛:治疗试验的批判性综述

Vestibular migraine: a critical review of treatment trials.

作者信息

Fotuhi Majid, Glaun Braeme, Quan Susan Y, Sofare Tzipora

机构信息

Center for Balance, Dizziness, and Vertigo, LifeBridge Health Brain & Spine Institute, 5051 Greenspring Avenue, Baltimore, MD 21209, USA.

出版信息

J Neurol. 2009 May;256(5):711-6. doi: 10.1007/s00415-009-5050-5. Epub 2009 Mar 1.

DOI:10.1007/s00415-009-5050-5
PMID:19252785
Abstract

Vestibular migraine (VM), also known as migraine-associated vertigo, is a common cause of dizziness in adults. We performed a comprehensive literature search regarding treatment for VM or migraine-associated vertigo during the period of 1990-2008 and used, individually or in combination, the search terms VM, migraine-associated vertigo, migraine-associated dizziness, migrainous vertigo, migraine and vertigo, migraine and disequilibrium, and headache and vertigo. We found nine publications that address treatment strategies for VM. One small randomized clinical trial found some benefit from the use of zolmitriptan for abortive treatment of VM. The other eight observational studies showed marginal improvement with migraine prophylactic medications such as nortriptyline, verapamil, or metoprolol. Until more specific treatment options become available, patients with VM need to be managed with similar prophylactic and abortive strategies as those used for migraine in adults.

摘要

前庭性偏头痛(VM),也被称为偏头痛相关性眩晕,是成人头晕的常见原因。我们对1990年至2008年期间关于VM或偏头痛相关性眩晕治疗的文献进行了全面检索,并单独或组合使用了检索词VM、偏头痛相关性眩晕、偏头痛相关性头晕、偏头痛性眩晕、偏头痛与眩晕、偏头痛与平衡失调以及头痛与眩晕。我们找到了9篇论述VM治疗策略的出版物。一项小型随机临床试验发现,使用佐米曲普坦进行VM的预防性治疗有一定益处。其他8项观察性研究表明,使用如去甲替林、维拉帕米或美托洛尔等偏头痛预防性药物有轻微改善。在有更具体的治疗选择之前,VM患者需要采用与成人偏头痛相同的预防性和预防性治疗策略进行管理。

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本文引用的文献

1
Vestibular paroxysmia: diagnostic features and medical treatment.前庭性阵发性眩晕:诊断特征与药物治疗
Neurology. 2008 Sep 23;71(13):1006-14. doi: 10.1212/01.wnl.0000326594.91291.f8.
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Epidemiology, risk factors, and treatment of chronic migraine: a focus on topiramate.慢性偏头痛的流行病学、危险因素及治疗:聚焦托吡酯
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Migraine-related vertigo: diagnosis and treatment.偏头痛相关性眩晕:诊断与治疗
前庭性偏头痛与晕动病易感性的关系。
Otol Neurotol. 2020 Sep;41(8):1116-1121. doi: 10.1097/MAO.0000000000002705.
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Effects of Vestibular Rehabilitation in the Management of a Vestibular Migraine: A Review.前庭康复训练在前庭性偏头痛管理中的作用:综述
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Vestibular Migraine.前庭性偏头痛
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Vestibular Migraine: Clinical Challenges and Opportunities for Multidisciplinarity.前庭性偏头痛:多学科面临的临床挑战与机遇
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Recent Advances in the Understanding of Vestibular Migraine.前庭性偏头痛认识的最新进展
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Distribution of 5-HT Receptors in Monkey Vestibular and Trigeminal Ganglion Cells.5-羟色胺受体在猴前庭神经节和三叉神经节细胞中的分布
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Prophylactic treatment of vestibular migraine.前庭性偏头痛的预防性治疗。
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Nimodipine in otolaryngology: from past evidence to clinical perspectives.尼莫地平在耳鼻喉科:从既往证据到临床展望
Acta Otorhinolaryngol Ital. 2015 Jun;35(3):135-45.
Curr Pain Headache Rep. 2007 Jun;11(3):217-26. doi: 10.1007/s11916-007-0193-5.
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Migraine-related vertigo: diagnostic criteria and prophylactic treatment.偏头痛相关性眩晕:诊断标准与预防性治疗
Laryngoscope. 2006 Oct;116(10):1782-6. doi: 10.1097/01.mlg.0000231302.77922.c5.
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Epidemiology of vestibular vertigo: a neurotologic survey of the general population.前庭性眩晕的流行病学:一项针对普通人群的神经耳科学调查。
Neurology. 2005 Sep 27;65(6):898-904. doi: 10.1212/01.wnl.0000175987.59991.3d.
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Use of topiramate (topamax) in a subgroup of migraine-vertigo patients with auditory symptoms.托吡酯(妥泰)在伴有听觉症状的偏头痛性眩晕患者亚组中的应用。
Ann N Y Acad Sci. 2005 Apr;1039:517-20. doi: 10.1196/annals.1325.057.
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Treatment of migraine related vertigo with lamotrigine an observational study.拉莫三嗪治疗偏头痛相关性眩晕的一项观察性研究
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Chronic migrainous vertigo.慢性偏头痛性眩晕
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Zolmitriptan for treatment of migrainous vertigo: a pilot randomized placebo-controlled trial.佐米曲普坦治疗偏头痛性眩晕:一项前瞻性随机安慰剂对照试验
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