Fotuhi Majid, Glaun Braeme, Quan Susan Y, Sofare Tzipora
Center for Balance, Dizziness, and Vertigo, LifeBridge Health Brain & Spine Institute, 5051 Greenspring Avenue, Baltimore, MD 21209, USA.
J Neurol. 2009 May;256(5):711-6. doi: 10.1007/s00415-009-5050-5. Epub 2009 Mar 1.
Vestibular migraine (VM), also known as migraine-associated vertigo, is a common cause of dizziness in adults. We performed a comprehensive literature search regarding treatment for VM or migraine-associated vertigo during the period of 1990-2008 and used, individually or in combination, the search terms VM, migraine-associated vertigo, migraine-associated dizziness, migrainous vertigo, migraine and vertigo, migraine and disequilibrium, and headache and vertigo. We found nine publications that address treatment strategies for VM. One small randomized clinical trial found some benefit from the use of zolmitriptan for abortive treatment of VM. The other eight observational studies showed marginal improvement with migraine prophylactic medications such as nortriptyline, verapamil, or metoprolol. Until more specific treatment options become available, patients with VM need to be managed with similar prophylactic and abortive strategies as those used for migraine in adults.
前庭性偏头痛(VM),也被称为偏头痛相关性眩晕,是成人头晕的常见原因。我们对1990年至2008年期间关于VM或偏头痛相关性眩晕治疗的文献进行了全面检索,并单独或组合使用了检索词VM、偏头痛相关性眩晕、偏头痛相关性头晕、偏头痛性眩晕、偏头痛与眩晕、偏头痛与平衡失调以及头痛与眩晕。我们找到了9篇论述VM治疗策略的出版物。一项小型随机临床试验发现,使用佐米曲普坦进行VM的预防性治疗有一定益处。其他8项观察性研究表明,使用如去甲替林、维拉帕米或美托洛尔等偏头痛预防性药物有轻微改善。在有更具体的治疗选择之前,VM患者需要采用与成人偏头痛相同的预防性和预防性治疗策略进行管理。