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超越眩晕:前庭性偏头痛的前庭、听觉和知觉症状。

Beyond Vertigo: Vestibular, Aural, and Perceptual Symptoms in Vestibular Migraine.

机构信息

Department of Neurology, Jefferson Headache Center, Thomas Jefferson University, 900 Walnut St., Ste 200, Philadelphia, PA, 19107, USA.

出版信息

Curr Pain Headache Rep. 2024 Jul;28(7):633-639. doi: 10.1007/s11916-024-01245-3. Epub 2024 May 23.

DOI:10.1007/s11916-024-01245-3
PMID:38780828
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11271338/
Abstract

PURPOSE

To review the vestibular, aural, and perceptual symptoms of vestibular migraine (VM) that may present alongside vertigo.

RECENT FINDINGS

Increased research attention to the wide spectrum of symptoms presenting in VM patients has improved understanding of this disorder, with recent identification of five different VM phenotypes. Research into the clinical overlap between VM and other chronic vestibular syndromes such as persistent postural-perceptual dizziness and mal-de-debarquement syndrome reveals a range of vestibular symptoms and hints at pathophysiological connections between migraine and vestibular dysfunction. Studies of migraine treatment for hearing loss suggest patients presenting with aural symptoms may have an underlying diagnosis of migraine and deserve a trial of migraine preventives. Research into the neurologic basis of the perceptual disorder Alice in Wonderland syndrome has revealed brain areas that are likely involved and may help explain its prevalence in VM patients. VM is a sensory processing disorder that presents with more than just vertigo. Understanding the range of potential symptoms improves diagnosis and treatment for migraine patients whose diagnosis may be missed when only the symptoms identified in the diagnostic criteria are considered.

摘要

目的

回顾前庭性偏头痛(VM)可能与眩晕同时出现的前庭、听觉和知觉症状。

最新发现

对 VM 患者表现出的广泛症状的研究关注度增加,提高了对这种疾病的认识,最近确定了五种不同的 VM 表型。对 VM 与持续性姿势感知性头晕和晕动病综合征等其他慢性前庭综合征之间的临床重叠的研究揭示了一系列前庭症状,并暗示偏头痛和前庭功能障碍之间存在病理生理学联系。对偏头痛治疗听力损失的研究表明,出现听觉症状的患者可能存在偏头痛的潜在诊断,值得尝试偏头痛预防药物。对知觉障碍“爱丽丝梦游仙境综合征”的神经基础的研究揭示了可能涉及的大脑区域,这可能有助于解释其在 VM 患者中的高患病率。VM 是一种感觉处理障碍,不仅仅表现为眩晕。了解潜在症状的范围有助于提高偏头痛患者的诊断和治疗,因为仅考虑诊断标准中确定的症状可能会漏诊这些患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37b9/11271338/c6bd2b8cd9d3/11916_2024_1245_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37b9/11271338/c6bd2b8cd9d3/11916_2024_1245_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37b9/11271338/c6bd2b8cd9d3/11916_2024_1245_Fig1_HTML.jpg

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本文引用的文献

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Phenotypes and clinical subgroups in vestibular migraine: a cross-sectional study with cluster analysis.前庭性偏头痛的表型与临床亚组:一项聚类分析的横断面研究
Neurol Sci. 2024 Mar;45(3):1209-1216. doi: 10.1007/s10072-023-07116-w. Epub 2023 Oct 16.
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Neuroimaging markers of Alice in Wonderland syndrome in patients with migraine with aura.有先兆偏头痛患者中爱丽丝梦游仙境综合征的神经影像学标志物。
Front Neurol. 2023 Aug 24;14:1210811. doi: 10.3389/fneur.2023.1210811. eCollection 2023.
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Management of Migraine-Associated Vestibulocochlear Disorders.
偏头痛相关性前庭蜗神经疾病的管理
Audiol Res. 2023 Jul 19;13(4):528-545. doi: 10.3390/audiolres13040047.
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Cluster and network analysis of non-headache symptoms in migraine patients reveals distinct subgroups based on onset age and vestibular-cochlear symptom interconnection.偏头痛患者非头痛症状的聚类和网络分析显示,基于发病年龄和前庭蜗症状相互联系可分为不同亚组。
Front Neurol. 2023 May 26;14:1184069. doi: 10.3389/fneur.2023.1184069. eCollection 2023.
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Early detection and monitoring of hearing loss in vestibular migraine: Extended high-frequency hearing.前庭性偏头痛中听力损失的早期检测与监测:扩展高频听力
Front Aging Neurosci. 2023 Jan 10;14:1090322. doi: 10.3389/fnagi.2022.1090322. eCollection 2022.
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Persistent Postural Perceptual Dizziness in Episodic Vestibular Disorders.发作性前庭疾病中的持续性姿势性感知性头晕
Audiol Res. 2022 Oct 27;12(6):589-595. doi: 10.3390/audiolres12060058.
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Functional connectivity alterations in migraineurs with Alice in Wonderland syndrome.患有爱丽丝梦游仙境综合征的偏头痛患者的功能连接改变
Neurol Sci. 2023 Jan;44(1):305-317. doi: 10.1007/s10072-022-06404-1. Epub 2022 Sep 17.
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Auditory Manifestations of Vestibular Migraine.前庭性偏头痛的听觉表现
Front Neurol. 2022 Jul 15;13:944001. doi: 10.3389/fneur.2022.944001. eCollection 2022.
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Vestibular migraine, demographic and clinical features of 415 patients: A multicenter study.415例患者的前庭性偏头痛:多中心研究的人口统计学和临床特征
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Risk of Vestibulocochlear Disorders in Patients with Migraine or Non-Migraine Headache.偏头痛或非偏头痛性头痛患者发生前庭蜗神经障碍的风险
J Pers Med. 2021 Dec 8;11(12):1331. doi: 10.3390/jpm11121331.