Souza-Oliveira Cecília, Escorsi-Rosset Sara, Bianchin Marino Muxfeldt, Terra Vera Cristina, Wichert-Ana Lauro, Machado Hélio Rubens, Sakamoto Américo Ceiki
Department of Neurology, Psychiatry and Psychology, Ribeirão Preto School of Medicine, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Childs Nerv Syst. 2009 Jul;25(7):875-80. doi: 10.1007/s00381-009-0839-1. Epub 2009 Feb 28.
In the present study, we evaluated the preoperative demographic, clinical, and neuropsychological variables that could predict postoperative seizure outcome in a group of pediatric epileptic patients.
We studied 40 consecutive pediatric patients, ages ranging from 6 to 16 years, that underwent resective surgery for the treatment of medically intractable epilepsy at the Clinical Hospital of Ribeirão Preto School of Medicine. We performed ictal electroencephalography (EEG), interictal EEG, magnetic resonance imaging (MRI), and a preoperative neuropsychological assessment in the presurgical workup.
The following factors were correlated with seizure outcome: (1) duration of epilepsy, (2) surgery localization, (3) localized Neuropsychological (NPS) Evaluation, (4) ictal EEG, (5) interictal EEG, and (6) MRI. Mental retardation, NPS tests, and the other demographic variables failed to correlate with seizure reduction.
The identification of predictor variables of epilepsy surgery outcome could improve the epileptic prognosis and guarantee the children's full potential development.
在本研究中，我们评估了一组小儿癫痫患者术前的人口统计学、临床和神经心理学变量，这些变量可预测术后癫痫发作结果。
我们研究了40例连续的小儿患者，年龄在6至16岁之间，他们在里贝朗普雷图医学院临床医院接受了切除性手术以治疗药物难治性癫痫。在术前检查中，我们进行了发作期脑电图（EEG）、发作间期EEG、磁共振成像（MRI）和术前神经心理学评估。
以下因素与癫痫发作结果相关：（1）癫痫持续时间，（2）手术定位，（3）局部神经心理学（NPS）评估，（4）发作期EEG，（5）发作间期EEG，以及（6）MRI。智力迟钝、NPS测试和其他人口统计学变量与癫痫发作减少无关。
确定癫痫手术结果的预测变量可以改善癫痫预后，并保证儿童的充分潜能发展。
