一类新型甾体激素的妇科应用：选择性孕激素受体调节剂

Gynaecological uses of a new class of steroids: the selective progesterone receptor modulators.

作者信息

Pintiaux Axelle, Chabbert-Buffet Nathalie, Foidart Jean-Michel

出版信息

Gynecol Endocrinol. 2009 Feb;25(2):67-73. doi: 10.1080/09513590802531120.

PMID:19253100

Abstract

Selective progesterone receptor modulators (SPRM) represent a new class of synthetic steroids, which can interact with the progesterone receptor (PR) and can exert agonist, antagonist or mixed effects on various progesterone target tissues in vivo. This review evaluates the actual and potential usefulness of SPRMs in gynaecology.

摘要

选择性孕激素受体调节剂（SPRM）是一类新型合成甾体，可与孕激素受体（PR）相互作用，并在体内对各种孕激素靶组织发挥激动剂、拮抗剂或混合效应。本综述评估了SPRM在妇科领域的实际和潜在用途。