Department of Obstetrics, Gynecology, and Reproductive Sciences, San Francisco General Hospital and Bixby Center for Global Reproductive Health, University of California, San Francisco, CA, USA.
Int J Womens Health. 2010 Aug 9;2:63-8. doi: 10.2147/ijwh.s6344.
Intrauterine progestins have many important current and potential gynecologic applications. This article describes the evidence for use of intrauterine progestin for common gynecologic conditions beyond its important role in contraception. The pharmacology of and selection criteria for use of the levonorgestrel intrauterine device is discussed, and the evidence for use of intrauterine progestin delivery for menorrhagia, endometriosis management, uterine fibroids, adenomyosis and endometrial hyperplasia is reviewed.
宫内孕激素在妇科领域有许多重要的当前和潜在应用。本文介绍了除避孕作用外,宫内孕激素在常见妇科疾病中的应用证据。讨论了左炔诺孕酮宫内节育器的药理学和使用选择标准,并回顾了宫内孕激素用于月经过多、子宫内膜异位症管理、子宫肌瘤、子宫腺肌病和子宫内膜增生的证据。