Nagoev B S, Bzhakhova F K
Klin Lab Diagn. 2009 Jan(1):13-5.
The prooxidative-antioxidative systems of plasma and blood corpuscles were evaluated in 151 patients with primary, secondary recent, secondary recurrent, and latent syphilis. The red blood cell levels of malonic dialdehyde, ceruloplasmin, and catalase were measured during the pathological process. The authors identified the following regularities: with active clinical manifestations of syphilis, there was a significant suppression of the blood antioxidative system and a substantial increase in the activity of the blood prooxidative system and blood corpuscles, with these parameters becoming normal after performed treatment. They also show it possible to use the tests of the blood prooxidative-antioxidative systems to evaluate the degree of the pathological process in patients with syphilis, as well as for prognostic purposes.
对151例原发性、继发性近期、继发性复发性和潜伏性梅毒患者的血浆和血细胞的促氧化-抗氧化系统进行了评估。在病理过程中测量了红细胞中丙二醛、铜蓝蛋白和过氧化氢酶的水平。作者发现了以下规律：梅毒有活跃临床表现时，血液抗氧化系统受到显著抑制，血液促氧化系统和血细胞活性大幅增加，治疗后这些参数恢复正常。他们还表明，血液促氧化-抗氧化系统检测可用于评估梅毒患者病理过程的程度以及预后。
