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[复发性病毒性疱疹感染患者脂质过氧化过程及抗氧化防御的强度]

[The intensity of processes of lipoperoxidation and antioxidant defense in patients with recurrent viral herpes infection].

作者信息

Nagoev B S, Kambachokova Z A

出版信息

Klin Lab Diagn. 2012 Mar(3):19-21.

PMID:22712286
Abstract

The article discusses some parameters of free radical metabolism of lymphocytes of blood plasma in 65 patients with recurrent virus herpes infection in course of disease. It is established that in patients occurs increasing of both of level of malonic dialdehyde and functional activity of neutrophils in blood plasma. On the background of these alterations, compensatory increase of activity of such antioxidant enzymes as ceruloplasmin and catalase is noted. The intensity of stationary derangement of free radical oxidation and antioxidant defense under recurrent virus herpes infection depended on the period of disease and severity of pathologic process.

摘要

本文讨论了65例复发性病毒性疱疹感染患者病程中血浆淋巴细胞自由基代谢的一些参数。结果表明,患者血浆中丙二醛水平和中性粒细胞功能活性均升高。在这些改变的背景下,观察到血浆中铜蓝蛋白和过氧化氢酶等抗氧化酶的活性代偿性增加。复发性病毒性疱疹感染时自由基氧化和抗氧化防御的稳态紊乱强度取决于病程和病理过程的严重程度。

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