Paudyal G, Shrestha M K, Meyer J J, Thapa R, Gurung R, Ruit S
Tilganga Eye Centre, Kathmandu, Nepal.
Nepal Med Coll J. 2008 Sep;10(3):160-3.
Diabetic retinopathy is a public health challenge in developing countries including Nepal and is not like other preventable or treatable causes of blindness. The aim of study was to estimate the prevalence of diabetic retinopathy following a community screening for diabetes. A community-based, cross sectional study was designed to screen for diabetes in people age > or =40 years in a semi-urban community of Kathmandu, Nepal. In those individuals with detected diabetes, a comprehensive eye examination was performed by an ophthalmologist and diabetic retinopathy was graded using a standard protocol. 1475 persons were screened for diabetes with a mean age of 54.7 +/- 12 years with sex ratio of 0.69 male per female. Thirty-four subjects were found to have impaired fasting glucose and sixty subjects had diabetes. The prevalence of diabetes mellitus was 4.1% (60) but 6.4% (94) had an abnormal blood sugar level. Fifty-seven diabetic patients visited at-Tilganga Eye Centre for ocular examination. Among examined patients, the prevalence of diabetic retinopathy was 19.3% (11). Only one person had clinically significant macular edema requiring laser therapy. The prevalence of hypertension and cataracts were the same among patients with and without diabetic retinopathy. The prevalence of diabetic retinopathy was low but one of sixteen newly diagnosed diabetics did have evidence of diabetic retinopathy. Eighty-four percent of known diabetics had never had their eyes examined for ocular complications. Community awareness and physician coordination should be emphasized to increase the eye examination rate.
糖尿病视网膜病变在包括尼泊尔在内的发展中国家是一项公共卫生挑战,与其他可预防或可治疗的失明原因不同。本研究的目的是评估在社区进行糖尿病筛查后糖尿病视网膜病变的患病率。一项基于社区的横断面研究旨在对尼泊尔加德满都一个半城市社区中年龄≥40岁的人群进行糖尿病筛查。在那些被检测出患有糖尿病的个体中,由眼科医生进行全面的眼部检查,并使用标准方案对糖尿病视网膜病变进行分级。对1475人进行了糖尿病筛查,平均年龄为54.7±12岁,男女比例为0.69。34名受试者空腹血糖受损,60名受试者患有糖尿病。糖尿病患病率为4.1%(60人),但血糖水平异常者占6.4%(94人)。57名糖尿病患者前往蒂尔甘加眼科中心进行眼部检查。在接受检查的患者中,糖尿病视网膜病变的患病率为19.3%(11人)。只有一人患有需要激光治疗的具有临床意义的黄斑水肿。有糖尿病视网膜病变和无糖尿病视网膜病变的患者中高血压和白内障的患病率相同。糖尿病视网膜病变的患病率较低,但每16名新诊断的糖尿病患者中有1人确实有糖尿病视网膜病变的证据。84%的已知糖尿病患者从未因眼部并发症接受过眼部检查。应强调社区意识和医生协作以提高眼部检查率。