Holst Alexandra Ioana, Hirschfelder Ursula, Holst Stefan
Department of Orthodontics, Friedrich-Alexander-University of Erlangen, Nuremberg, Germany.
Cleft Palate Craniofac J. 2009 Mar;46(2):215-9. doi: 10.1597/07-015.1. Epub 2007 Nov 15.
Cherubism is an autosomal-dominant syndrome characterized by bilateral maxillomandibular bony degeneration, fibrous connective tissue hyperplasia, and displacement of permanent tooth germs. Reossification of the cystic lumen occurs spontaneously, but dislocated teeth must be realigned orthodontically. Advancements in virtual 3D reconstruction of anatomic structures based on computed tomography (CT) or cone beam CT data have provided for more predictable individual treatment planning. We evaluated two software programs for making densitometry and volume measurements of cystic areas in the mandibles, and for 3D visualization of permanent tooth germs within the cystic lumen, in two siblings with cherubism.
颌骨肥大症是一种常染色体显性综合征，其特征为双侧上颌下颌骨骨质退化、纤维结缔组织增生以及恒牙胚移位。囊性腔会自发地重新骨化，但错位的牙齿必须通过正畸进行重新排列。基于计算机断层扫描（CT）或锥形束CT数据对解剖结构进行虚拟三维重建技术的进步，为更具可预测性的个体化治疗方案制定提供了可能。我们评估了两款软件程序，用于对两名患有颌骨肥大症的兄弟姐妹的下颌囊性区域进行密度测定和体积测量，以及对囊性腔内的恒牙胚进行三维可视化。
