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cherubism:成人全景和 CT 特征。

Cherubism: panoramic and CT features in adults.

机构信息

Department of Maxillofacial Radiology, Faculty of Dentistry, University of Oslo, Blindern, Oslo, Norway;

出版信息

Dentomaxillofac Radiol. 2013;42(10):20130034. doi: 10.1259/dmfr.20130034. Epub 2013 Sep 18.

DOI:10.1259/dmfr.20130034
PMID:24048692
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3853512/
Abstract

OBJECTIVES

To describe the panoramic radiographic and CT features of cherubism in an unselected series of 15 adults.

METHODS

In this cross-sectional study, 15 individuals aged 29-84 years with familial non-syndromal molecularly confirmed cherubism were examined with panoramic radiography and CT. Bone abnormalities were analysed and described.

RESULTS

11 (73%) of the 15 adults had mandibular abnormalities. These abnormalities ranged from subtly detectable to severe, and were less prevalent and expansive but could be rather similar to the characteristic image features in children. Unilocular radiolucencies were more common than multilocular radiolucencies, and a specific feature of these abnormalities was that they were exclusively found in the anterior mandible.

CONCLUSIONS

The radiographic and CT abnormalities of cherubism in adults were frequent and extremely heterogeneous, with some distinct features.

摘要

目的

描述 15 例未经选择的成人 cherubism 的全景 X 线和 CT 特征。

方法

在这项横断面研究中,对 15 名年龄 29-84 岁的、具有家族性非综合征分子确诊 cherubism 的个体进行了全景 X 线和 CT 检查。分析和描述了骨异常。

结果

15 名成人中 11 名(73%)存在下颌骨异常。这些异常从细微可检测到严重不等,并且不那么普遍和广泛,但可能与儿童的特征性图像特征相当相似。单房性透亮区比多房性透亮区更常见,这些异常的一个特定特征是它们仅发生在前下颌骨。

结论

成人 cherubism 的影像学和 CT 异常很常见且极其多样,具有一些明显的特征。

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Characterization of a Norwegian cherubism cohort; molecular genetic findings, oral manifestations and quality of life.挪威 cherubism 队列的特征;分子遗传学发现、口腔表现及生活质量
Eur J Med Genet. 2013 Mar;56(3):131-7. doi: 10.1016/j.ejmg.2012.12.008. Epub 2013 Jan 5.
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Gorlin-Goltz syndrome--a medical condition requiring a multidisciplinary approach.戈林-高茨综合征——一种需要多学科方法的医疗状况。
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Cherubism: best clinical practice. cherubism:最佳临床实践。
Orphanet J Rare Dis. 2012 May 24;7 Suppl 1(Suppl 1):S6. doi: 10.1186/1750-1172-7-S1-S6.
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Postpubertal nonfamilial cherubism and teeth transposition.青春期后非家族性颌骨肥大症与牙齿易位
J Craniofac Surg. 2010 Sep;21(5):1575-7. doi: 10.1097/SCS.0b013e3181ecc529.
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Idiopathic bilateral central giant cell reparative granuloma of jaws: a case report and literature review.特发性双侧颌骨中央巨细胞修复性肉芽肿:一例报告及文献复习
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Diagnostic potential of 3D-data-based reconstruction software: an analysis of the rare disease pattern of cherubism.基于三维数据的重建软件的诊断潜力: cherubism罕见病模式分析
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Familial cherubism: the experience of the Moscow Central Institute for Stomatology and Maxillo-Facial Surgery.家族性颌骨多囊病:莫斯科中央口腔颌面外科研究所的经验
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