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创伤性下肢截肢者中完整髋关节和膝关节骨关节炎的患病率。

The prevalence of osteoarthritis of the intact hip and knee among traumatic leg amputees.

作者信息

Struyf Pieter A, van Heugten Caroline M, Hitters Minou W, Smeets Rob J

机构信息

Rehabilitation Centre Blixembosch, Eindhoven, The Netherlands.

出版信息

Arch Phys Med Rehabil. 2009 Mar;90(3):440-6. doi: 10.1016/j.apmr.2008.08.220.

DOI:10.1016/j.apmr.2008.08.220
PMID:19254609
Abstract

OBJECTIVE

To determine the prevalence of osteoarthritis (OA) in the knee and/or hip of the intact leg among traumatic leg amputees compared with the general population and its relationship with amputation level, time since amputation, age, and mobility.

DESIGN

Cross-sectional observational study.

SETTING

Outpatient population of 2 Dutch rehabilitation centers.

PARTICIPANTS

Patients (N=78) with a unilateral traumatic transtibial amputation, knee disarticulation, or transfemoral amputation of at least 5 years ago; ability to walk with a prosthesis; older than 18 years of age; and able to understand Dutch. Patients were excluded if they had bilateral amputations, other pathologies of the knee or hip, or central neurologic pathologies.

INTERVENTIONS

Not applicable.

MAIN OUTCOME MEASURE

The prevalence of OA.

RESULTS

The prevalence of knee OA was 27% (men 28.3%, women 22.2%) and hip OA was 14% (men 15.3%, women 11.1%). This was higher compared with the general population (knee OA men 1.58%, women 1.33%, hip OA men 1.13%, women 0.98%, age adjusted). No significant relationships between the prevalence of OA and level of amputation, time since amputation, mobility, and age were found.

CONCLUSIONS

The prevalence of OA is significantly greater for both the knee and hip in the traumatic leg amputee population. No specific risk factors were identified. Although no specific risk factors in this specific population could be identified, it might be relevant to apply commonly known strategies to prevent OA as soon as possible after the amputation.

摘要

目的

确定创伤性下肢截肢者健侧膝关节和/或髋关节骨关节炎(OA)的患病率,并与普通人群进行比较,同时研究其与截肢水平、截肢时间、年龄和活动能力的关系。

设计

横断面观察性研究。

地点

荷兰两家康复中心的门诊患者。

参与者

至少在5年前进行单侧创伤性经胫骨截肢、膝关节离断或经股骨截肢的患者(N = 78);能够使用假肢行走;年龄大于18岁;能够理解荷兰语。若患者为双侧截肢、膝关节或髋关节有其他病变或患有中枢神经系统疾病,则排除在外。

干预措施

不适用。

主要观察指标

OA的患病率。

结果

膝关节OA的患病率为27%(男性28.3%,女性22.2%),髋关节OA的患病率为14%(男性15.3%,女性11.1%)。与普通人群相比更高(年龄调整后,膝关节OA男性1.58%,女性1.33%;髋关节OA男性1.13%,女性0.98%)。未发现OA患病率与截肢水平、截肢时间、活动能力和年龄之间存在显著关系。

结论

创伤性下肢截肢人群中膝关节和髋关节OA的患病率均显著更高。未确定具体危险因素。尽管在这一特定人群中未发现具体危险因素,但在截肢后尽早应用常见的预防OA策略可能具有重要意义。

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