Department of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii 96813, USA.
Heart Lung. 2009 Mar-Apr;38(2):163-6. doi: 10.1016/j.hrtlng.2008.04.006. Epub 2008 Aug 23.
We report an 81-year-old Japanese patient with takotsubo cardiomyopathy associated with syncope with the possibility that the latter event evoked the former condition. Initial investigations revealed elevation of cardiac enzymes and electrocardiography changes consistent with acute myocardial infarction. The patient subsequently underwent cardiac catheterization that revealed left ventricular apical ballooning and decreased left ventricular ejection fraction without significant coronary artery lesions. A marked elevation in plasma norepinephrine, as a result of baroreflex unloading associated with profound hypotension or frank baroreflex failure, may well have caused takotsubo cardiomyopathy.
我们报告了一例 81 岁的日本患者，其患有 Takotsubo 心肌病并伴有晕厥，后者可能诱发了前者。初步检查显示心肌酶升高和符合急性心肌梗死的心电图变化。随后患者进行了心脏导管插入术，显示左心室心尖球囊样变和左心室射血分数降低，没有明显的冠状动脉病变。显著升高的血浆去甲肾上腺素可能是由于严重低血压或明显的压力反射衰竭引起的压力反射卸载导致了 Takotsubo 心肌病。
