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解释美国阿拉伯裔美国人早产风险较低的原因:对617451例分娩的分析。

Explaining the low risk of preterm birth among arab americans in the United States: an analysis of 617451 births.

作者信息

El-Sayed Abdulrahman M, Galea Sandro

机构信息

BS, University of Michigan School of Public Health, Department of Epidemiology, 109 Observatory St, Ann Arbor, MI 48109, USA.

出版信息

Pediatrics. 2009 Mar;123(3):e438-45. doi: 10.1542/peds.2008-1634.

DOI:10.1542/peds.2008-1634
PMID:19254980
Abstract

OBJECTIVES

Arab Americans have a lower risk for preterm birth than white Americans. We assessed factors that may contribute to the association between ethnicity and preterm birth risk in Michigan, the state with the largest concentration of Arab Americans in the United States. Factors assessed as potential contributors to the ethnicity/preterm birth risk association were maternal age, parity, education, marital status, tobacco use, and maternal birthplace.

METHODS

Data were collected about all births in Michigan between 2000 and 2005. Stratified analyses, trivariate analyses, and manual stepwise logistic regression model building were used to assess potential contributors to the ethnicity/preterm birth risk association.

RESULTS

Arab ethnicity was associated with lower preterm birth risk compared with non-Arab white subjects in the unadjusted model. Maternal birthplace inside or outside the United States explained 0.17 of the difference in preterm birth risk between Arab ethnicity and non-Arab white mothers; ethnic differences in marital status and tobacco use explained less of the observed ethnic difference in preterm birth risk. In the final model adjusted for all explanatory variables, Arab ethnicity was no longer associated with preterm birth risk.

CONCLUSIONS

Maternal birthplace, marital status, and tobacco use may contribute to the preterm birth risk difference between Arab ethnicity and non-Arab white mothers. Additional work is needed to consider the mechanisms relating factors such as maternal birthplace and marital status to ethnic differences in preterm birth risk.

摘要

目的

阿拉伯裔美国人的早产风险低于美国白人。我们评估了可能导致种族与密歇根州早产风险之间存在关联的因素,密歇根州是美国阿拉伯裔美国人最集中的州。被评估为种族/早产风险关联潜在因素的有产妇年龄、产次、教育程度、婚姻状况、吸烟情况以及产妇出生地。

方法

收集了2000年至2005年密歇根州所有分娩的数据。采用分层分析、三变量分析以及手动逐步逻辑回归模型构建来评估种族/早产风险关联的潜在因素。

结果

在未调整模型中,与非阿拉伯白人相比,阿拉伯种族与较低的早产风险相关。美国境内外的产妇出生地解释了阿拉伯种族和非阿拉伯白人母亲早产风险差异的0.17;婚姻状况和吸烟情况的种族差异对观察到的早产风险种族差异的解释较少。在对所有解释变量进行调整的最终模型中,阿拉伯种族与早产风险不再相关。

结论

产妇出生地、婚姻状况和吸烟情况可能导致阿拉伯种族和非阿拉伯白人母亲之间早产风险的差异。需要进一步开展工作来考虑诸如产妇出生地和婚姻状况等因素与早产风险种族差异之间的关联机制。

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