Scott Jean, Drum Melissa, Reader Al, Nusstein John, Beck Mike
Division of Endodontics, College of Dentistry, The Ohio State University, Columbus 43210, USA.
J Am Dent Assoc. 2009 Mar;140(3):318-24. doi: 10.14219/jada.archive.2009.0161.
Previous studies have shown declining rates of pulpal anesthesia over 60-minute periods in patients who have received 1.8 milliliters of 2 percent lidocaine with 1:100,000 epinephrine in the maxillary lateral incisor.
The authors conducted a prospective, randomized, single-blind, crossover study comparing the degree of pulpal anesthesia obtained in 40 adult subjects with two sets of maxillary lateral incisor infiltrations, given in two separate appointments: an initial infiltration of 1.8 mL of 2 percent lidocaine with 1:100,000 epinephrine plus a repeated infiltration of the same anesthetic and dose given 30 minutes after the initial infiltration, and an initial infiltration of 1.8 mL of 2 percent lidocaine with 1:100,000 epinephrine plus a mock repeated infiltration given 30 minutes after the initial infiltration. The authors used an electric pulp tester to test the lateral incisor for anesthesia in two-minute cycles for 90 minutes after the injection.
The repeated infiltration improved pulpal anesthesia significantly in the maxillary lateral incisor in the period from 37 through 90 minutes postinjection.
A repeated infiltration of 1.8 mL of 2 percent lidocaine with 1:100,000 epinephrine given 30 minutes after the initial infiltration significantly improved the duration of pulpal anesthesia in the maxillary lateral incisor.
先前的研究表明，在上颌侧切牙接受1.8毫升2%利多卡因加1:100,000肾上腺素的患者中，60分钟内牙髓麻醉率下降。
作者进行了一项前瞻性、随机、单盲、交叉研究，比较40名成年受试者在上颌侧切牙进行两组浸润麻醉时获得的牙髓麻醉程度，这两组麻醉在两次单独的就诊中进行：第一次浸润使用1.8毫升2%利多卡因加1:100,000肾上腺素，在第一次浸润30分钟后重复浸润相同的麻醉剂和剂量，以及第一次浸润使用1.8毫升2%利多卡因加1:100,000肾上腺素，在第一次浸润30分钟后进行模拟重复浸润。作者使用牙髓电活力测试仪在注射后90分钟内以两分钟为周期测试侧切牙的麻醉情况。
在注射后37至90分钟期间，重复浸润显著改善了上颌侧切牙的牙髓麻醉。
在第一次浸润30分钟后重复浸润1.8毫升2%利多卡因加1:100,000肾上腺素，显著延长了上颌侧切牙牙髓麻醉的持续时间。
