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在初次和非感染性翻修全髋关节置换术中,引流尖端培养对关节感染的预测价值:一项前瞻性对比研究及文献复习。

Prognostic value of suction drain tip culture in determining joint infection in primary and non-infected revision total hip arthroplasty: a prospective comparative study and review of the literature.

机构信息

1st Orthopaedic Department, Aristotle University of Thessaloniki, G.Papanikolaou Hospital, Exohi, 57010, Thessaloniki, Greece.

出版信息

Arch Orthop Trauma Surg. 2009 Dec;129(12):1645-9. doi: 10.1007/s00402-009-0844-6. Epub 2009 Mar 3.

Abstract

INTRODUCTION

Closed suction drainage in joint replacement surgery has been considered to carry an obvious risk of bacteria invasion. Previous studies have shown controversial results regarding the role of suction drain culture in predicting artificial joint infection. Furthermore, the efficacy of the method has not been established in revision total hip or knee arthroplasty.

MATERIALS AND METHODS

Suction drain tips from 110 patients who underwent 73 primary and 37 revision non-infected total hip arthroplasties were prospectively cultured. The drains removed at 48 h postoperatively. The patients had an average age of 64.3 years (range 25-81 years) and followed up for 2-4 years (average 2.8 years).

RESULTS

Positive cultures were identified in two primary (2.74%) and six revision (16.22%) total hip replacements (p = 0.017). The most frequently isolated microorganisms were Staphylococcus aureus (3 cases) and S. epidermidis (2 cases). Resistance to perioperative antibiotics was found in three out of eight isolated pathogens. However, no infection was recorded in any of the eight patients whose cultures found positive.

CONCLUSION

Although suction drains are more often contaminated in revision total hip arthroplasty, the prognostic value of the method in determining joint infection is very limited and its routine use is not supported from the clinical data.

摘要

引言

关节置换术中使用闭式引流被认为会明显增加细菌入侵的风险。既往研究表明,引流液培养在预测人工关节感染方面的作用结果存在争议。此外,该方法在翻修全髋关节或膝关节置换术中的疗效尚未得到证实。

材料与方法

前瞻性培养了 110 例接受 73 例初次和 37 例非感染性翻修全髋关节置换术患者的引流管尖端。术后 48 小时拔出引流管。患者平均年龄 64.3 岁(25-81 岁),随访 2-4 年(平均 2.8 年)。

结果

初次全髋关节置换术中有 2 例(2.74%)和 6 例(16.22%)翻修全髋关节置换术的引流液培养阳性(p = 0.017)。最常分离到的微生物为金黄色葡萄球菌(3 例)和表皮葡萄球菌(2 例)。8 株分离病原体中有 3 株对围手术期抗生素耐药。然而,培养阳性的 8 例患者中均未发生感染。

结论

尽管在翻修全髋关节置换术中引流管更常受到污染,但该方法在确定关节感染方面的预后价值非常有限,且从临床数据来看,不支持常规使用该方法。

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