Kershenobich D, Borovoy J, Guevara L, Male R, Alcocer J
Departamento de Gastroenterología, Instituto Nacional de la Nutrición "Salvador Zubirán", Vasco de Quiroga No. 15, Tlalpan, C.P. 14000 México, DF.
Rev Invest Clin. 1990 Jul;42 Suppl:28-31.
The cytokines are proteins synthetized by lymphoid and monocyte/macrophage system cells in response to a wide variety of infectious stimulus, featuring bacterial endotoxins. These proteins have immunoregulatory effects and have been implicated in inflammation and fibrosis. In this review we refer to the interleukin-1, interleukin-6 and tumor necrosis factor because of their elevated basal levels in acute and chronic hepatopaties and in response to lipopolisacharide mainly in alcoholic liver disease.
细胞因子是淋巴细胞和单核细胞/巨噬细胞系统细胞针对多种感染刺激（包括细菌内毒素）合成的蛋白质。这些蛋白质具有免疫调节作用，并与炎症和纤维化有关。在本综述中，我们提及白细胞介素-1、白细胞介素-6和肿瘤坏死因子，因为它们在急性和慢性肝病中基础水平升高，且主要在酒精性肝病中对脂多糖有反应。
