Chuka-Okosa C M, Uche N J, Kizor-Akaraiwe N N
Department of Ophthalmology, University of Nigeria Teaching Hospital (U.N.T.H.), Enugu, South-Eastern Nigeria.
West Afr J Med. 2008 Jul;27(3):144-7.
Orbito-ocular neoplasms are important causes of ophthalmic morbidity and mortality. Various reports have shown that they occur more commonly among Africans than Caucasians. In this era of HIV pandemic, an increase in the frequency of AIDS-related orbito-ocular neoplasms has also been reported.
This study was carried out to determine the pattern of orbito-ocular tumours in Enugu, South-Eastern Nigeria and to compare it with the findings from earlier studies in the same area, other parts of Nigeria and other countries.
In a retrospective, non-comparative case series study the records of all the cases of orbito-ocular neoplasms seen in the Histopathology departments of the two tertiary multidisciplinary hospitals with major eye clinics in Enugu (ParkLane Specialist and University of Nigeria Teaching Hospitals) between January 2001 and August 2005 were analysed for types of tumours, frequency of occurrence, sex and age of patients.
A total of 43 cases were analysed. There were 17 males and 26 females (M: F-l:1.4). Retinoblastoma was the most commonly occurring neoplasm accounting for 25.6% of all the tumours; followed by squamous cell carcinoma of the conjunctiva which was seen in 5 (11.6%) of cases. Squamous papilloma and Burkitt's lymphoma each accounting for 9.3% of the tumours in the series were the third most commonly occurring ones.
In spite of the limitations of the study our findings suggest that the spectrum of orbito-ocular neoplasms has generally remained the same in Enugu, South-Eastern Nigeria as well as in other parts of the country.
眼眶-眼肿瘤是导致眼科疾病和死亡的重要原因。各种报告显示，它们在非洲人中比在高加索人中更常见。在艾滋病毒大流行的这个时代，也有报告称与艾滋病相关的眼眶-眼肿瘤的发病率有所增加。
本研究旨在确定尼日利亚东南部埃努古眼眶-眼肿瘤的发病模式，并将其与该地区早期研究、尼日利亚其他地区以及其他国家的研究结果进行比较。
在一项回顾性、非对比性病例系列研究中，分析了2001年1月至2005年8月期间在埃努古设有主要眼科诊所的两家三级多学科医院（帕克巷专科医院和尼日利亚大学教学医院）组织病理学科室诊治的所有眼眶-眼肿瘤病例的记录，包括肿瘤类型、发病率、患者性别和年龄。
共分析了43例病例。男性17例，女性26例（男：女 = 1:1.4）。视网膜母细胞瘤是最常见的肿瘤，占所有肿瘤的25.6%；其次是结膜鳞状细胞癌，有5例（11.6%）。鳞状乳头状瘤和伯基特淋巴瘤各占该系列肿瘤的9.3%，是第三常见的肿瘤。
尽管本研究存在局限性，但我们的研究结果表明，尼日利亚东南部埃努古以及该国其他地区眼眶-眼肿瘤的种类总体上保持不变。
