Chekmarev Sergei F
Institute of Thermophysics, 630090 Novosibirsk, Russia and Department of Physics, Novosibirsk State University, 630090 Novosibirsk, Russia.
Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Dec;78(6 Pt 2):066113. doi: 10.1103/PhysRevE.78.066113. Epub 2008 Dec 23.
It is shown that the information entropy based on waiting-time distributions (WTDs) offers a natural and robust measure of nonexponentiality of the distributions in the form of the Schrödinger-Brillouin negentropy, or equivalently the Kullback-Leibler divergence, and has a straightforward interpretation in terms of transition state theory. Other measures of nonexponentiality of WTDs, based on comparison of the standard deviation and the median with the mean waiting time, are also discussed. The theoretical analysis is illustrated with results from protein folding studies.
结果表明，基于等待时间分布（WTDs）的信息熵以薛定谔 - 布里渊负熵的形式，或者等效地以库尔贝克 - 莱布勒散度的形式，提供了一种自然且稳健的分布非指数性度量，并且在过渡态理论方面具有直接的解释。还讨论了基于标准差和中位数与平均等待时间比较的WTDs非指数性的其他度量。通过蛋白质折叠研究的结果对理论分析进行了说明。
