Laughlin E H
School of Primary Medical Care, University of Alabama, Huntsville.
South Med J. 1991 Oct;84(10):1205-9. doi: 10.1097/00007611-199110000-00011.
Three members of a family with Peutz-Jeghers syndrome had intussusception due to intestinal hamartomas. In addition, the grandfather had carcinoma of the jejunum, and the granddaughter had benign ovarian sex cord/stromal tumor causing sexual precocity. Benign and malignant tumors, not often associated with Peutz-Jeghers syndrome, pose a further threat in addition to the gastrointestinal bleeding and obstruction that often complicate this inherited syndrome.
患有黑斑息肉综合征的一个家族中的三名成员因肠道错构瘤发生肠套叠。此外，祖父患有空肠癌，孙女患有导致性早熟的良性卵巢性索/间质瘤。除了常使这种遗传性综合征复杂化的胃肠道出血和梗阻外，与黑斑息肉综合征不常相关的良性和恶性肿瘤构成了进一步的威胁。
