Gebäck Tobias, Koumoutsakos Petros
Computational Science, ETH Zürich, Universitätstrasse 6, CAB H69,2, ETH Zürich, CH-8092 Zürich, Switzerland.
BMC Bioinformatics. 2009 Mar 3;10:75. doi: 10.1186/1471-2105-10-75.
Despite significant progress in imaging technologies, the efficient detection of edges and elongated features in images of intracellular and multicellular structures acquired using light or electron microscopy is a challenging and time consuming task in many laboratories.
We present a novel method, based on the discrete curvelet transform, to extract a directional field from the image that indicates the location and direction of the edges. This directional field is then processed using the non-maximal suppression and thresholding steps of the Canny algorithm to trace along the edges and mark them. Optionally, the edges may then be extended along the directions given by the curvelets to provide a more connected edge map. We compare our scheme to the Canny edge detector and an edge detector based on Gabor filters, and show that our scheme performs better in detecting larger, elongated structures possibly composed of several step or ridge edges.
The proposed curvelet based edge detection is a novel and competitive approach for imaging problems. We expect that the methodology and the accompanying software will facilitate and improve edge detection in images available using light or electron microscopy.
尽管成像技术取得了显著进展,但在许多实验室中,利用光学或电子显微镜获取的细胞内和多细胞结构图像中,高效检测边缘和细长特征仍是一项具有挑战性且耗时的任务。
我们提出了一种基于离散曲波变换的新方法,从图像中提取一个指示边缘位置和方向的方向场。然后使用Canny算法的非极大值抑制和阈值化步骤对该方向场进行处理,以沿着边缘进行追踪并标记它们。可选地,然后可以沿着曲波给出的方向扩展边缘,以提供更连贯的边缘图。我们将我们的方案与Canny边缘检测器和基于Gabor滤波器的边缘检测器进行比较,并表明我们的方案在检测可能由多个阶跃或脊状边缘组成的更大、更细长的结构方面表现更好。
所提出的基于曲波的边缘检测是一种针对成像问题的新颖且有竞争力的方法。我们期望该方法和配套软件将有助于并改善利用光学或电子显微镜获取的图像中的边缘检测。