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茶的生物活性成分:癌症、炎症与行为

Bioactive components of tea: cancer, inflammation and behavior.

作者信息

de Mejia Elvira Gonzalez, Ramirez-Mares Marco Vinicio, Puangpraphant Sirima

机构信息

Department of Food Science and Human Nutrition, University of Illinois-Urbana-Champaign, 1201 W. Gregory Drive, Urbana, IL 61801, USA.

出版信息

Brain Behav Immun. 2009 Aug;23(6):721-31. doi: 10.1016/j.bbi.2009.02.013. Epub 2009 Mar 1.

Abstract

Tea is one of the most widely consumed beverages worldwide. Several studies have suggested that catechins and theaflavins found in tea may reduce the risk of various types of cancers. Major advances have been made to understand the molecular events leading to cancer prevention; however, the evidence is not conclusive. Evidence from pre-clinical and clinical studies also suggests that persistent inflammation can progress to cancer. Several possible mechanisms of action may explain the cancer preventive aspects of tea components specifically anti-inflammatory effects. In regards to brain health, green tea catechins have been recognized as multifunctional compounds for neuroprotection with beneficial effects on vascular function and mental performance. Theanine, a unique amino acid in tea, enhances cognition in humans and has neuroprotective effects. Human interventional studies with well characterized tea products are needed.

摘要

茶是全球消费最为广泛的饮品之一。多项研究表明,茶中含有的儿茶素和茶黄素可能降低多种癌症的风险。在了解导致癌症预防的分子事件方面已取得重大进展;然而,证据并不确凿。临床前和临床研究的证据还表明,持续性炎症可能会发展为癌症。几种可能的作用机制或许可以解释茶成分预防癌症的方面,特别是抗炎作用。关于脑健康,绿茶儿茶素已被公认为具有神经保护作用的多功能化合物,对血管功能和心理表现有益。茶氨酸是茶中一种独特的氨基酸,可提高人类认知能力并具有神经保护作用。需要对特征明确的茶产品进行人体干预研究。

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