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伊朗一项关于饮料摄入与多发性硬化症风险的病例对照研究。

A case-control study of drinking beverages and the risk of multiple sclerosis in Iran.

机构信息

Department of Biostatistics and Epidemiology, Musculoskeletal Rehabilitation Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Department of Regenerative Biomedicine, Royan Institute for Stem Cell Biology and Technology, ACCR, Tehran, Iran.

出版信息

J Health Popul Nutr. 2023 Mar 23;42(1):22. doi: 10.1186/s41043-023-00364-8.

Abstract

BACKGROUND

There is no study in the world on the relationship between consuming black and green tea as beverages containing polyphenols and the risk of MS. This study aimed to determine the association between the consumption of green and black tea, coffee, non-alcoholic beer, milk, fruit juices and carbonated beverages with the risk of MS.

METHODS AND MATERIALS

This case-control study was performed on 150 patients with MS and 300 healthy individuals as a control group among patients who were referred to the ophthalmology ward of a referral hospital in Ahvaz with the groups matching for age. The data collection tool was a researcher-made questionnaire including demographic information and beverage consumption. Analysis was performed using univariate and multiple logistic regression models.

RESULTS

The mean age of patients at the time of diagnosis was 38.55 ± 8.88 years. The results showed that drinking milk (OR = 5.46), natural juice (OR = 2.49), and carbonated beverages (OR = 16.17) were associated with an increased chance of developing MS. However, drinking non-alcoholic beer (OR = 0.48), black tea (OR = 0.20), green tea (OR = 0.29) and coffee (OR = 0.07) were associated with a reduced chance of developing MS.

CONCLUSION

The results show that drinking black and green tea, non-alcoholic beer, and coffee are associated with a decrease in the chance of developing MS. The results of this study can be used to design interventional research and to change people's lifestyles to prevent MS.

摘要

背景

目前世界上尚无研究关注多酚类饮料,如饮用黑茶和绿茶与多发性硬化症(MS)风险之间的关系。本研究旨在确定饮用绿茶和黑茶、咖啡、无酒精啤酒、牛奶、果汁和碳酸饮料与 MS 风险之间的关联。

方法和材料

这项病例对照研究共纳入 150 名 MS 患者和 300 名健康对照者,患者均来自阿瓦兹转诊医院眼科病房,按年龄与对照组相匹配。数据收集工具是研究者自制的问卷,包括人口统计学信息和饮料消费情况。采用单变量和多变量逻辑回归模型进行分析。

结果

患者诊断时的平均年龄为 38.55±8.88 岁。结果显示,饮用牛奶(OR=5.46)、天然果汁(OR=2.49)和碳酸饮料(OR=16.17)与 MS 发病几率增加相关。然而,饮用无酒精啤酒(OR=0.48)、黑茶(OR=0.20)、绿茶(OR=0.29)和咖啡(OR=0.07)与 MS 发病几率降低相关。

结论

结果表明,饮用黑茶和绿茶、无酒精啤酒和咖啡与 MS 发病几率降低有关。本研究结果可用于设计干预性研究并改变人们的生活方式,以预防 MS。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3ff/10037787/c08b2b4b572d/41043_2023_364_Fig1_HTML.jpg

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