Nakakura Shunsuke, Imamura Hitoshi, Nakamura Takao
Department of Ophthalmology, Saiseikai Gose Hospital, Mimuro, Gose, Japan.
Optom Vis Sci. 2009 Apr;86(4):e404-6. doi: 10.1097/OPX.0b013e318199d226.
Postoperative intraocular pressure elevation is the most common complication to occur after penetrating keratoplasty (PKP). When topical antiglaucoma drops or oral systemic medication cannot lower this pressure, surgical intervention is necessary. However, surgery cannot yet be performed that does not adversely affect the graft, and better surgical treatments are required.
A 62-year-old man had undergone PKP to treat bullous keratopathy in the left eye. Secondary glaucoma occurred early postoperation and was controlled through topical antiglaucoma eye drops, medication, and the decreasing use of topical steroids. However, 7 months postsurgery, intraocular pressure (IOP) in the eye re-elevated to 42 mm Hg (Goldmann applanation tonometer). Selective laser trabeculoplasty was performed inferiorly for 6 h and then added selective laser trabeculoplasty performed superiorly for 6 h, 1 week later. Complete slit lamp biomicroscopy, visual acuity, IOP, gonioscopy, and mydriatic funduscopy were performed pre- and posttreatment for 6 months.
IOP decreased from 42 to 27 mm Hg 1 week after selective laser trabeculoplasty (SLT) (inferior 180 degrees). After an additional superior 180 degrees SLT performed 2 weeks after this, IOP decreased to 15 mm Hg. Six months later, IOP was stable at 18 mm Hg, and graft rejection, new peripheral anterior synechiae, and visual acuity disturbance were not observed.
IOP elevation after PKP was successfully treated with SLT. SLT will become a valuable therapeutic method that limits invasive surgery for treatment of secondary glaucoma after PKP.
穿透性角膜移植术(PKP)后眼压升高是最常见的并发症。当局部抗青光眼滴眼液或口服全身药物无法降低眼压时,就需要进行手术干预。然而,目前尚无不对移植片产生不利影响的手术方法,因此需要更好的手术治疗方案。
一名62岁男性因左眼大泡性角膜病变接受了PKP手术。术后早期发生继发性青光眼,通过局部抗青光眼滴眼液、药物治疗以及减少局部类固醇的使用得以控制。然而,术后7个月,患眼眼压(IOP)再次升高至42 mmHg(Goldmann压平眼压计测量)。首先对下方进行选择性激光小梁成形术治疗6小时,1周后再对上方进行选择性激光小梁成形术治疗6小时。治疗前后6个月内均进行了完整的裂隙灯显微镜检查、视力、眼压、前房角镜检查和散瞳眼底检查。
选择性激光小梁成形术(SLT)(下方180度)后1周,眼压从42 mmHg降至27 mmHg。在此之后2周,再对上方180度进行SLT治疗,眼压降至15 mmHg。6个月后,眼压稳定在18 mmHg,未观察到移植片排斥反应、新的周边前粘连和视力障碍。
PKP术后眼压升高通过SLT治疗成功。SLT将成为一种有价值的治疗方法,可减少PKP术后继发性青光眼的侵入性手术治疗。