Chisholm Jacob A, Jamieson Glyn G, Lally Carolyn J, Devitt Peter G, Game Philip A, Watson David I
Department of Surgery, Flinders Medical Centre, Flinders University, Room 3D211, Bedford Park, South Australia 5042, Australia.
J Gastrointest Surg. 2009 Jun;13(6):1064-70. doi: 10.1007/s11605-009-0837-3. Epub 2009 Mar 4.
Obesity has long been considered to be a predisposing factor for gastroesophageal reflux. It is also thought to predispose patients to a poorer clinical outcome following antireflux surgery. This study examined the effect of body mass index (BMI) on clinical outcomes following laparoscopic antireflux surgery.
Patients were included if they had undergone a laparoscopic fundoplication, their presurgical BMI was known, and they had been followed for at least 12 months after surgery. The clinical outcome was determined using a structured questionnaire, and this was applied yearly after surgery. Patients were divided into four groups according to BMI: normal weight (BMI < 25), overweight (BMI 25-29.9), obese (BMI 30-34.9), and morbidly obese (BMI > or = 35). The most recent clinical outcome data was analyzed for each BMI group.
Patients, 481, were studied. One hundred three (21%) had a normal BMI, 208 (43%) were overweight, 115 (24%) were obese, and 55 (12%) were morbidly obese. Mean follow-up was 7.5 years. Conversion to an open operation and requirement for revision surgery were not influenced by preoperative weight. Operating time was longer in obese patients (mean 86 vs 75 min). Clinical outcomes improved following surgery regardless of BMI.
Preoperative BMI does not influence the clinical outcome following laparoscopic antireflux surgery. Obesity is not a contraindication for laparoscopic fundoplication.
长期以来,肥胖一直被认为是胃食管反流的一个诱发因素。人们还认为肥胖会使患者在抗反流手术后临床结局更差。本研究探讨了体重指数(BMI)对腹腔镜抗反流手术后临床结局的影响。
纳入接受了腹腔镜胃底折叠术、已知术前BMI且术后至少随访12个月的患者。使用结构化问卷确定临床结局,术后每年应用该问卷。根据BMI将患者分为四组:正常体重(BMI<25)、超重(BMI 25-29.9)、肥胖(BMI 30-34.9)和病态肥胖(BMI≥35)。分析每个BMI组的最新临床结局数据。
共研究了481例患者。103例(21%)BMI正常,208例(43%)超重,115例(24%)肥胖,55例(12%)病态肥胖。平均随访7.5年。转为开放手术和翻修手术的需求不受术前体重影响。肥胖患者的手术时间更长(平均86分钟对75分钟)。无论BMI如何,术后临床结局均有改善。
术前BMI不影响腹腔镜抗反流手术后的临床结局。肥胖不是腹腔镜胃底折叠术的禁忌证。