Opsomer G, de Kruif A
Tijdschr Diergeneeskd. 1991 Aug 15;116(15-16):773-6.
The case of a male calf affected with bovine congenital porphyria is reported in the present paper. The diagnosis was based on the specific and pathognomonic symptoms: lesions of the pale parts of the skin due to photosensitization, brownish discolouration of the teeth and urine, overall wasting and retardation of growth. The diagnosis was verified by analysis of the blood and urine: in the blood we found a high concentration of protoporphyrins (269 micrograms/l) and a rather low cell count (19 per cent), in the urine high concentrations of uro- and coproporphyrins (3340 and 2550 micrograms/l respectively) were determined. As there is no effective treatment for this disease, it was advised to keep the animal indoors and fatten it. The farmer did not follow this advice. The calf died within a few months.
本文报道了一例患先天性牛卟啉症的雄性犊牛病例。诊断基于特定的典型症状:因光过敏导致皮肤浅色部位出现病变、牙齿和尿液呈褐色、整体消瘦以及生长发育迟缓。通过对血液和尿液的分析证实了诊断:血液中发现原卟啉浓度很高(269微克/升)且细胞计数相当低(19%),尿液中测定出高浓度的尿卟啉和粪卟啉(分别为3340和2550微克/升)。由于这种疾病没有有效的治疗方法,建议将动物饲养在室内并进行育肥。养殖户未听从这一建议。这头犊牛在几个月内死亡。