Mut Melike, Hazer Burcu, Narin Firat, Akalan Nejat, Ozgen Tunçalp
Hacettepe University, Neurosurgery, Ankara, Turkey.
Turk Neurosurg. 2009 Jan;19(1):36-41.
Aspiration of the abscess cavity versus excision of capsule are still in debate for the capsulated, large, superficially located abscesses.
Twenty patients who had large, solitary, capsulated, and superficially located lobar abscesses were analyzed retrospectively to compare the efficiency of two different surgical approaches and their impact on postoperative antibiotic use and the length of hospital stay.
Nine patients underwent the capsule excision and 11 patients had the aspiration of their abscesses. There were no differences in terms of age, sex, location of abscesses, and radiographic features. There were 3 residual/recurrence in the aspiration group, who needed a second aspiration whereas; no residual/recurrence was observed in the excision group. Postoperative utilization of antibiotics was significantly less in the excision group (Mean: 26.7 days in the excision group vs. 46.6 days in aspiration group). Length of hospital stay for the purpose of iv antibiotic administration was significantly shorter in the excision group in close correlation with iv antibiotic use.
Our study demonstrated that excision of abscess capsule was superior to aspiration in terms of efficiency of surgical intervention and postoperative cost of the treatment in a highly selected group of brain abscesses.
对于有包膜的、较大的浅表性脓肿,脓肿腔穿刺抽吸与包膜切除仍存在争议。
回顾性分析20例患有大的、单发的、有包膜的浅表性叶脓肿的患者,比较两种不同手术方法的疗效及其对术后抗生素使用和住院时间的影响。
9例患者接受了包膜切除术,11例患者进行了脓肿抽吸术。在年龄、性别、脓肿位置和影像学特征方面无差异。抽吸组有3例残留/复发,需要再次抽吸;而切除组未观察到残留/复发。切除组术后抗生素使用明显较少(切除组平均26.7天,抽吸组平均46.6天)。与静脉注射抗生素使用密切相关,切除组静脉注射抗生素治疗的住院时间明显较短。
我们的研究表明,在一组高度选择的脑脓肿患者中,脓肿包膜切除在手术干预效率和术后治疗费用方面优于抽吸术。