Harris Lauren, Raducanu Ioana, Low Hu Liang
Neurosurgery, Queen's Hospital, London, GBR.
Microbiology, Queen's Hospital, London, GBR.
Cureus. 2021 Aug 27;13(8):e17498. doi: 10.7759/cureus.17498. eCollection 2021 Aug.
Brain abscesses due to species account for 1-2% of all cerebral abscesses, often in immunosuppressed individuals, with a mortality three times higher than other cerebral abscesses. Early diagnosis and management are vital for good outcomes. We report a case of a right frontal brain abscess in an immunosuppressed 38-year-old female. She presented with headaches, confusion, memory deficits, and personality change. She remained systemically well, with normal inflammatory markers. She underwent two open surgical drainages, with excision of the abscess wall. She made an excellent recovery with minimal edema and no contrast enhancement on imaging at eight weeks postoperatively. Management of brain abscess includes a prompt diagnosis with direct microscopic examination and initiation of correct antibiotic therapy for good outcomes. We recommend open surgical resection, including excision of the abscess wall, followed by long-term antimicrobial therapy, to enhance the rate of recovery.
由该菌种引起的脑脓肿占所有脑脓肿的1%-2%，常见于免疫抑制个体，其死亡率比其他脑脓肿高三倍。早期诊断和治疗对良好预后至关重要。我们报告一例38岁免疫抑制女性的右额叶脑脓肿病例。她表现为头痛、意识模糊、记忆缺陷和性格改变。她全身状况良好，炎症指标正常。她接受了两次开放性手术引流，并切除了脓肿壁。术后八周，她恢复良好，水肿轻微，影像学检查无强化。脑脓肿的治疗包括通过直接显微镜检查迅速诊断，并开始正确的抗生素治疗以获得良好预后。我们建议进行开放性手术切除，包括切除脓肿壁，然后进行长期抗菌治疗，以提高恢复率。
