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桡动脉桥血流量优于隐静脉在壁后侧。

Radial artery graft flowmetry is better than saphenous vein on postero-lateral wall.

机构信息

Cardiac Surgery Unit, Magna Graecia University of Catanzaro, Italy.

出版信息

Int J Cardiol. 2010 Aug 20;143(2):158-64. doi: 10.1016/j.ijcard.2009.02.008. Epub 2009 Mar 4.

Abstract

BACKGROUND

Although general agreement exists on internal mammary graft as the first conduit, the second choice is still questioned. Despite radial artery (RA) grafting has been suggested, saphenous veins (SV) continue to be extensively used.

METHODS

A prospective series of isolated RA-CABG (150 patients) or SV-CABG (180 patients), performed either off-pump (OP-CABG) and on-pump (CPB-CABG), in diabetics and non-diabetics, in elderly and young patients, during the last 5-years at a single institution were evaluated. RA was harvested with harmonic scalpel, flowmetry was performed with a transit-time flowmeter (TTF). Graft flow reserve (GFR) was calculated with intra-aortic balloon-pump. Follow-up was collected by outpatient clinic database or by telephone interview with general practitioners.

RESULTS

The 2 groups showed comparable preoperative and intraoperative variables. Mortality, morbidity, myocardial infarction, troponin I leakage, and echocardiographic parameters were comparable (p=NS). RA-CABG demonstrated significantly higher TTF maximum, mean and minimum flow (p<.001) with lower Pulsatility Index (p<.001), either in the circumflex and the right coronaries. Compared to SVG-grafting, significantly higher GFR was found in RA-CABG on the circumflex (p=.001) and right (p=.028) coronaries. 38.1+/-0.9 SE months follow-up resulted in higher survival and freedom from cardiac events in RA-CABG. Better TTF and GFR were demonstrated in OP-CABG, CPB-CABG, diabetics, non-diabetics, either on the circumflex and right coronary systems (p<.05). Better mean flow was detected in RA-CABG on the circumflex in the elderly (p=.04) and the young (p=.05).

CONCLUSIONS

RA-CABG demonstrated better TTF and GFR results compared to SV-CABG. These data may contribute to explain the survival benefit of arterial revascularization already reported.

摘要

背景

尽管人们普遍认为内乳动脉是首选移植物,但对于第二选择仍存在争议。尽管有人建议使用桡动脉(RA)进行移植,但大隐静脉(SV)仍被广泛使用。

方法

在过去 5 年中,我们在一家机构中对接受了 RA-CABG(150 例患者)或 SV-CABG(180 例患者)手术的糖尿病患者和非糖尿病患者、老年患者和年轻患者进行了前瞻性系列研究,这些患者接受了非体外循环(OP-CABG)和体外循环(CPB-CABG)。RA 采用超声刀采集,流量采用瞬态流量仪(TTF)测量。用主动脉内球囊泵测量移植血管的血流储备(GFR)。通过门诊数据库或与全科医生进行电话访谈收集随访信息。

结果

两组患者的术前和术中变量具有可比性。死亡率、发病率、心肌梗死、肌钙蛋白 I 漏出和超声心动图参数均无差异(p=NS)。RA-CABG 显示 TT 最大、平均和最小流量明显更高(p<.001),搏动指数明显更低(p<.001),无论是在回旋支还是右冠状动脉。与 SVG 移植相比,RA-CABG 在回旋支(p=.001)和右冠状动脉(p=.028)上的 GFR 明显更高。38.1+/-0.9 SE 个月的随访结果显示,RA-CABG 的存活率和无心脏事件发生率更高。OP-CABG、CPB-CABG、糖尿病患者和非糖尿病患者的 TTF 和 GFR 均优于 RA-CABG,回旋支和右冠状动脉系统的结果均如此(p<.05)。RA-CABG 在回旋支上的平均流量在老年患者(p=.04)和年轻患者(p=.05)中更高。

结论

与 SV-CABG 相比,RA-CABG 的 TTF 和 GFR 结果更好。这些数据可能有助于解释已经报道的动脉血运重建的生存获益。

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