Mourot L, Boussuges A, Campo P, Maunier S, Debussche X, Blanc P
EA 3920 and IFR133, Université de Franche Comté, Physiologie, Faculté de Médecine, Besançon, France.
Diabetes Res Clin Pract. 2009 May;84(2):138-44. doi: 10.1016/j.diabres.2009.02.001. Epub 2009 Mar 4.
The effect of a cardiovascular rehabilitation program on arterial compliance in type 2 diabetes mellitus with coronary disease was studied.
Hemodynamic data and arterial compliance were measured with a tonometer (HDI/Pulse wave CR-2000) in coronary artery disease patients with (n=32) and without (n=24) type 2 diabetes before and after a 6-week multidisciplinary cardiac rehabilitation program.
A decrease in heart rate and an increase in stroke volume without significant change in resting cardiac output were obtained in diabetic patients. Arterial compliance of both small and large arteries was significantly increased. In 10 diabetic patients, this increase could be related to an increase in the anti-hypertensive treatment and to the decreased blood pressure. In the 22 remainders, the small artery compliance was significantly increased independently of blood pressure change.
Exercise training as well as optimization of diabetes and dyslipidemia treatment could explain the improvement of arterial compliance. If these changes are long-lasting and if they improve prognosis remains to be evaluated.
研究心血管康复计划对伴有冠心病的2型糖尿病患者动脉顺应性的影响。
使用眼压计（HDI/脉搏波CR-2000）在一项为期6周的多学科心脏康复计划前后，测量患有（n=32）和未患有（n=24）2型糖尿病的冠心病患者的血流动力学数据和动脉顺应性。
糖尿病患者心率降低，每搏输出量增加，静息心输出量无显著变化。小动脉和大动脉的动脉顺应性均显著增加。在10名糖尿病患者中，这种增加可能与抗高血压治疗的增加和血压降低有关。在其余22名患者中，小动脉顺应性显著增加，与血压变化无关。
运动训练以及糖尿病和血脂异常治疗的优化可以解释动脉顺应性的改善。这些变化是否持久以及是否改善预后仍有待评估。
